A new study suggests that a vaccine commonly used to prevent shingles may also lower dementia risk in older adults. Published in Nature, the research found that people vaccinated against shingles had about a 20% lower chance of developing dementia over seven years. The findings add another reason for adults aged 50 and above to consider shingles vaccination, alongside preventing a painful rash and nerve complications.
For Thai readers, the implications are meaningful. Thailand’s population is aging, with more seniors at risk of dementia. If confirmed, the potential brain-health benefits of the shingles vaccine could support public health goals in the country. The Welsh-based study tracked roughly 280,000 medical records, comparing individuals who received the first-generation shingles vaccine with those who did not because of age-based eligibility.
Lead researcher Dr. Pascal Geldsetzer from Stanford University described the findings as robust and noted that women, who generally face higher dementia risk, may gain substantial protection. Collaborating experts highlight a potential link between the varicella-zoster virus and dementia risk, reinforcing the idea that vaccination could help safeguard brain health as people age.
Shingles is caused by the varicella-zoster virus, which lies dormant after chickenpox. When immunity wanes, the virus can reactivate, causing painful rashes and possible nerve complications. Some research has linked viral reactivation with inflammation and vascular injury—factors associated with cognitive decline and brain changes.
Data from the study point to a protective association between shingles vaccination and dementia risk. While the exact mechanisms remain under investigation, experts say reducing viral activity may contribute to better brain health in later life.
Thailand could consider incorporating these insights into public health planning. Expanding shingles vaccination campaigns might address both the immediate burden of shingles and long-term cognitive health, especially as vaccination rates in eligible populations remain below targets.
Researchers note ongoing work to evaluate newer vaccines, such as Shingrix, which offer higher protection against shingles. In the meantime, recommendations for maintaining brain health remain consistent: stay cognitively engaged, maintain social connections, and manage risk factors like blood pressure and diabetes.
Thailand’s cultural emphasis on family health provides a practical context for adopting vaccination as a broader health strategy. Families are encouraged to discuss options with healthcare providers to protect both current well-being and long-term cognitive health.