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One Dose of Ashwagandha Seen to Give Brainpower a Boost, New Study Finds

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A recent scientific study suggests that taking just a single dose of ashwagandha, a traditional herbal remedy used extensively in Ayurvedic medicine, could offer a noticeable enhancement to cognitive performance and mood—effects visible as quickly as one hour after ingestion and consistent over a month of supplementation. These promising findings, published in the peer-reviewed journal Nutrients, have stirred significant interest among health-conscious Thais and supplement enthusiasts worldwide (PsyPost).

Ashwagandha, or Withania somnifera, has long been revered as a tonic in Ayurveda, the ancient Indian system of health and wellness. Known in Thai as สมุนไพรอาชวกันดา and sometimes called “Indian ginseng,” ashwagandha is botanically unrelated to ginseng but is valued for its ability to bolster resilience and manage stress, or adaptogenic properties. Its root and, less commonly, the leaves, are the primary sources of medicinal extract, used both in traditional herbal preparations and in modern dietary supplements, readily available in Thailand’s health stores and pharmacies.

The research led by Megan Leonard and colleagues was designed to explore if a standardized, low daily dose of liposomal ashwagandha—a specially formulated type believed to increase absorption—could quickly and measurably influence brain function and emotional state in healthy young adults. The study recruited 59 volunteers, averaging 23 years old, split evenly between men and women. Participants were randomly assigned to receive either 225 mg of liposomal ashwagandha extract or a placebo each day for 30 days, using capsules identical in appearance to ensure a double-blind methodology (reference).

To evaluate cognitive performance, researchers employed the Computerized Mental Performance Assessment System (COMPASS), alongside mood assessments via the Profile of Mood States, at three key points: before supplementation, one hour after the initial dose, and after 30 days of daily use. The results revealed a striking pattern. Not only did those in the ashwagandha group perform better in memory, attention, vigilance, and executive function tasks compared to the placebo group, they also reported significantly lower feelings of tension and fatigue. The improvements appeared after just one hour—a finding that grabbed headlines for its implications on acute, rather than just chronic, supplementation (NutraIngredients).

“Our results support the idea that ashwagandha supplementation at this dose may improve memory, attention, vigilance, and executive function, while reducing tension and fatigue in healthy younger individuals,” the authors concluded (PsyPost). However, they also cautioned: “This study was limited to a relatively small, healthy, young cohort, and there’s a need for more research in broader populations.”

This breakthrough is meaningful for Thais, particularly students, young professionals, or anyone seeking safe and effective cognitive enhancement strategies—popularly known in Thailand as “brain booster” supplements. Ashwagandha-based products already feature heavily in Thai wellness markets. Still, skepticism remains; experts from previous research stress that while ashwagandha is generally regarded as safe when used appropriately, scientific evidence for its efficacy across all purported uses is still developing (Wikipedia).

Dr. Surachai Phongpanich, a neurologist from Chulalongkorn University, explains, “While traditional herbs like ashwagandha show exciting early results, it’s vital that Thai consumers look for products supported by robust scientific studies, checking for quality and certification, as well as potential drug interactions.” Thai consumers are known for their pragmatic approach to herbal medicine, with an increasing emphasis on evidence-based use, particularly among urban millennials and Generation Z.

The popularity of ashwagandha reflects a wider global trend where ancient remedies are being re-examined with modern scientific rigor. In fact, recent randomized controlled trials conducted in both Eastern and Western contexts have documented ashwagandha’s potential to reduce stress, improve sleep, and now, acutely enhance cognition—though results can vary depending on the preparation, dosage, and population studied (PubMed, PMC9565281), (Business Insider). Interestingly, one prior study found a 400mg dose improved working memory and reaction times, corroborating aspects of these latest findings (NutraIngredients).

Traditional Thai medicine, like its Indian counterpart, has its own pharmacopoeia of brain-boosting herbs, such as “bakopa monnieri” (พรมมิ) and “ginkgo biloba” (แปะก๊วย). Ashwagandha’s rising popularity among urban Thais reflects both cosmopolitan curiosity and an eagerness to blend ancient wisdom with cutting-edge science—a hallmark of modern Thai consumer culture.

Despite its growing reputation, experts urge caution. Ashwagandha supplements are not a substitute for a healthy lifestyle, nor for established medical treatments for serious cognitive issues. Side effects are rare but can include digestive upset and drowsiness, particularly at higher doses. There can also be interactions with certain medications or underlying health conditions (CNET). Furthermore, products sold in Thai markets may vary in quality and concentration, as regulatory oversight can differ, making it especially important to purchase from reputable sources.

On the horizon, continued research should shed more light on whether ashwagandha could benefit older adults, those with mild cognitive impairment, or individuals under chronic stress, expanding beyond the current findings focused on healthy young people (PubMed). If substantiated, this would position the herb as a powerful, low-risk tool in the growing field of nutritional cognitive enhancement—the much-discussed “nootropics” movement.

To harness potential benefits, Thai readers interested in trying ashwagandha should first consult a healthcare professional, especially if they have ongoing health issues or use prescription medication. Opt for standardized products, preferably those that clearly label the amount of ashwagandha extract per dose (ideally matching the 225–400 mg used in scientific studies). Avoid unverified health claims and do not exceed recommended doses—a principle known locally as “ใช้แต่พอดี” (chai tae paw dee, “use only as needed”). Above all, remember that good sleep, balanced nutrition, regular exercise, and mental engagement remain the foundations of sharp thinking and wellbeing.

For the scientifically minded, this growing body of research highlights the importance of scrutinizing the claims of seemingly “miracle” supplements, balancing open-mindedness with evidence-based caution. As Thailand continues to integrate global health trends, ashwagandha’s story demonstrates how วัฒนธรรมไทย (Thai culture) thoughtfully adapts ancient wisdom to modern life—for better brain health, and a balanced future.

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Medical Disclaimer: This article is for informational purposes only and should not be considered medical advice. Always consult with qualified healthcare professionals before making decisions about your health.