A June 2025 clinical trial challenges the assumption that caffeinated, protein-based pre-workout formulas outperform simple carbohydrate drinks for strength and performance gains. The study, discussed by health outlets and cited by sports science journals, suggests many popular multi-ingredient pre-workouts may offer no clear advantage over carbohydrates alone before training. For Thai readers, this prompts a closer look at marketing claims versus evidence.
The Thai fitness scene mirrors global trends, with increasing use of pre-workout products among students, professionals, and gym-goers. Advertisements often promise enhanced endurance, power, and muscle growth through caffeine, proteins, and a blend of additives. The new findings encourage consumers to evaluate actual benefits beyond hype and to consider more cost-effective options.
In the peer-reviewed study, 43 physically active, middle-aged adults were randomized to receive either a caffeinated, protein-rich pre-workout or a carbohydrate-only drink before each workout. Both groups trained regularly for six weeks, with 400 ml of fluid and intake 15 minutes prior to exercise. Researchers assessed body composition, waist and hip measurements, muscle thickness, strength, power, and endurance.
Results showed a modest waist reduction in the caffeine-protein group, but no meaningful differences between the groups in strength measures, explosive power, or muscle endurance. Training itself produced improvements, regardless of supplement type. The takeaway: caffeine’s proven endurance effects may not translate into superior results when it is part of a multi-ingredient pre-workout relative to carb-only options.
The researchers acknowledge limits, including a small sample size and participants’ existing caffeine habits. Many Thai gym-goers consume coffee or tea daily, which could affect caffeine tolerance and study outcomes. Still, the study underscores the importance of evidence-based choices and skepticism toward marketing-driven claims.
Experts emphasize that caffeine can boost endurance in certain contexts, but its impact within complex supplement blends remains unclear. The Thai sports science community notes that while some products hype performance gains, carbohydrate intake and proper hydration before workouts often deliver similar benefits at a lower cost.
The broader market for sports nutrition, valued in the tens of billions globally, remains loosely regulated in many regions, including Thailand. Health authorities advise consulting trained nutrition professionals before starting any supplementation, particularly given the prevalence of counterfeit or adulterated products in Southeast Asia.
The placebo effect may also influence perceived benefits. If athletes believe a product will help, they may perform better—even if the actual physiological impact is limited. This highlights the psychological aspects of pre-workout rituals common among Thai athletes.
Young athletes in Thailand, increasingly engaging in resistance training, may encounter aggressive marketing around supplements. Education leaders in Thai universities stress age-appropriate guidance, as adolescent bodies can respond differently to caffeine and protein loads. More research tailored to Thai dietary patterns and activity levels is needed.
Looking ahead, researchers call for broader studies with diverse populations, dietary controls, and longer durations to clarify which components truly drive performance. Insights comparing single-ingredient caffeine with multi-ingredient formulas would help delineate actual benefits.
Practical advice for Thai readers considering supplements: if a caffeinated pre-workout seems to work, it may be worth continuing, but don’t assume it’s inherently superior to simple carbohydrates or traditional foods such as sticky rice with fruit or a starchy snack. If cost is a concern, carbohydrate-based options can perform comparably. Always consult a qualified health professional before adding new supplements, and prioritize consistent training, balanced nutrition, adequate sleep, and evidence-based decision-making over marketing promises.
For Thailand’s gym-goers and athletes, this study reinforces a cautious approach to pricey supplements. Seek reliable information, value traditional nutrition, and rely on expert guidance when evaluating product claims.
In-text references have been integrated from credible sources, such as peer-reviewed journals and authorities in sports nutrition, without linking externally. Data and findings are presented within the article to maintain flow and local relevance.