A six-year study presented at ENDO 2025 challenges the view that aging alone governs men’s sexual health. Researchers found that even modest rises in blood sugar, rather than age or testosterone alone, are linked to declines in sperm quality, erectile function, and libido. The findings underscore the importance of metabolic health for men’s sexual vitality in Thailand and beyond.
Traditionally, discussions about declining male sexual and reproductive health have focused on hormones and aging. The new study, led by a senior endocrinologist, suggests that subtle metabolic changes—especially small increases in blood sugar—may play a larger role than previously recognized. “Although age and testosterone have long been linked to changes in sexual health, our findings show these shifts align more closely with modest rises in blood sugar and other metabolic changes,” the lead researcher noted. The takeaway: lifestyle management and regular blood sugar monitoring could help preserve sexual health with age.
The study, called FAME 2.0, followed 117 men aged 18 to 85 over six years. At baseline, participants had no diabetes, heart disease, or cancer. Researchers evaluated semen quality, hormone levels, erectile function, body mass index, and HbA1c, a marker of average blood sugar. Results showed that blood sugar levels below diabetes thresholds—HbA1c under 6.5%—were associated with lower sperm motility and weaker erectile function. Testosterone levels did not directly drive erectile performance, though they remained linked to self-rated libido.
These insights are particularly relevant for Thai men, where metabolic risks are rising with changing lifestyles. Thailand faces a growing burden of metabolic diseases: national health data show significant diabetes prevalence and many undiagnosed prediabetes cases. Regional differences exist, with urban lifestyles contributing to higher sugar intake and sedentary behavior. Diets influenced by processed foods and sugary beverages are increasingly common in Bangkok and expanding provinces, affecting metabolic health and, potentially, sexual vitality.
In Thai culture, conversations about male sexual health are often discreet, sometimes fueling reliance on herbal remedies or untested supplements. The new research invites open dialogue and proactive care. Clinicians in Bangkok and across Thailand emphasize the value of early detection of metabolic risks and routine blood sugar monitoring as cost-effective public health measures. An Bangkok endocrinologist highlighted that prevention—through dietary guidance and regular physical activity—should start well before symptoms appear.
Historically, rapid urbanization in Thailand has reshaped eating patterns. While traditional meals remain central, Western snacks and sugary drinks are widely available. The World Health Organization notes that average sugar intake in Thailand exceeds recommended limits, with sugary beverages being a major source. Public health campaigns have made strides against diabetes and obesity, yet younger men may not realize that sugar-rich diets can affect sexual health even before overt disease develops.
Looking ahead, FAME 2.0 could spur a new era in men’s health awareness in Asia and Thailand. Medical experts advocate routine screening for early blood sugar elevations in men presenting sexual health concerns, even if diabetes has not yet been diagnosed. Practical steps include regular HbA1c checks, lifestyle counseling to reduce sugar intake, and increased physical activity. Thai researchers are exploring local longitudinal studies to understand how cultural, dietary, and genetic factors influence metabolic risk.
Bottom line: managing blood sugar emerges as a practical, powerful approach to maintaining men’s sexual health as they age. Thai readers can take proactive steps now—limit added sugars, stay active, and pursue regular health check-ups. Open, stigma-free conversations with families, employers, and healthcare providers can support healthier choices and reduce the impact of metabolic risk on sexual vitality.
For guidance on sugar management and sexual health, consult Thailand’s Ministry of Public Health and local hospitals, along with reputable public health resources on diabetes and metabolic syndrome.