A new scientific perspective says regular exercise may slow or reverse biological aging. (Exercise as a geroprotector: focusing on epigenetic aging)
The review links exercise to changes in DNA markers called epigenetic clocks. (Exercise as a geroprotector: focusing on epigenetic aging)
The team frames exercise as a possible geroprotector. (SciTechDaily summary)
Epigenetic age tracks DNA methylation patterns. (Exercise as a geroprotector: focusing on epigenetic aging)
Researchers use these patterns as biological age markers. (Exercise as a geroprotector: focusing on epigenetic aging)
These clocks give a different view than chronological age. (Exercise as a geroprotector: focusing on epigenetic aging)
The review explains key exercise terms. (Exercise as a geroprotector: focusing on epigenetic aging)
Physical activity means any body movement that burns energy. (Exercise as a geroprotector: focusing on epigenetic aging)
Exercise is planned and goal-directed physical activity. (Exercise as a geroprotector: focusing on epigenetic aging)
Physical fitness describes attributes like strength and endurance. (Exercise as a geroprotector: focusing on epigenetic aging)
The authors say structured exercise shows the strongest effects. (Exercise as a geroprotector: focusing on epigenetic aging)
Moderate-to-vigorous exercise may trigger molecular benefits. (Exercise as a geroprotector: focusing on epigenetic aging)
The review cites animal experiments that support the idea. (Exercise as a geroprotector: focusing on epigenetic aging)
Mouse studies showed exercise reduced age-related DNA changes in muscle. (Exercise as a geroprotector: focusing on epigenetic aging)
Human trials also reported reductions in epigenetic age after training. (Exercise as a geroprotector: focusing on epigenetic aging)
One small trial found a two-year reduction in epigenetic age. (Exercise as a geroprotector: focusing on epigenetic aging)
That trial involved combined aerobic and strength training for eight weeks. (Exercise as a geroprotector: focusing on epigenetic aging)
Cardiorespiratory fitness correlated with slower epigenetic aging in older men. (Exercise as a geroprotector: focusing on epigenetic aging)
The review highlights bodybuilders and elite athletes. (Exercise as a geroprotector: focusing on epigenetic aging)
Athletes showed lower epigenetic ages than non-athletes. (Exercise as a geroprotector: focusing on epigenetic aging)
The authors say fitness delays aging across organs. (Exercise as a geroprotector: focusing on epigenetic aging)
They list the heart, liver, fat tissue, and gut as affected organs. (Exercise as a geroprotector: focusing on epigenetic aging)
The gut microbiome may link fitness and epigenetic age. (Exercise as a geroprotector: focusing on epigenetic aging)
The review calls for personalized exercise programs. (Exercise as a geroprotector: focusing on epigenetic aging)
The authors say some people respond more strongly to training. (Exercise as a geroprotector: focusing on epigenetic aging)
They urge standardized methods for future research. (Exercise as a geroprotector: focusing on epigenetic aging)
Researchers must unify how they measure activity and aging. (Exercise as a geroprotector: focusing on epigenetic aging)
They recommend diverse study populations by age and ethnicity. (Exercise as a geroprotector: focusing on epigenetic aging)
The review notes limits in current epigenetic clocks. (Exercise as a geroprotector: focusing on epigenetic aging)
They call for causal clocks tied to health outcomes. (Exercise as a geroprotector: focusing on epigenetic aging)
The authors discuss mechanisms that link exercise to DNA methylation. (Exercise as a geroprotector: focusing on epigenetic aging)
They highlight mitochondrial and metabolic pathways as candidates. (Exercise as a geroprotector: focusing on epigenetic aging)
The review notes acute exercise changes DNA methylation in muscle. (Exercise as a geroprotector: focusing on epigenetic aging)
Long-term training may change the methylome more durably. (Exercise as a geroprotector: focusing on epigenetic aging)
The paper appears in the journal Aging in July 2025. (Exercise as a geroprotector: focusing on epigenetic aging)
Public summaries circulated in science media this month. (SciTechDaily summary)
Experts outside the study praised the review for clarity. (News-Medical coverage)
The authors wrote that fitness delays epigenetic aging in multiple organs. (Exercise as a geroprotector: focusing on epigenetic aging)
They described exercise as a promising tool for extending healthspan. (Exercise as a geroprotector: focusing on epigenetic aging)
The review lists specific human studies and interventions. (Exercise as a geroprotector: focusing on epigenetic aging)
One cited study used combined aerobic and strength training for eight weeks. (Exercise as a geroprotector: focusing on epigenetic aging)
That study found decreased biological age in blood and muscle. (Exercise as a geroprotector: focusing on epigenetic aging)
Another study linked higher VO2 measures to slower epigenetic aging. (Exercise as a geroprotector: focusing on epigenetic aging)
The review distinguishes leisure activity from structured exercise. (Exercise as a geroprotector: focusing on epigenetic aging)
It says leisure activity may help but structured exercise works better. (Exercise as a geroprotector: focusing on epigenetic aging)
The authors also warn that occupational activity may differ in effect. (Exercise as a geroprotector: focusing on epigenetic aging)
Sedentary behavior may accelerate epigenetic aging. (Exercise as a geroprotector: focusing on epigenetic aging)
Breaking up sitting time could benefit biological age markers. (Exercise as a geroprotector: focusing on epigenetic aging)
The review emphasizes cardiorespiratory fitness as a key predictor. (Exercise as a geroprotector: focusing on epigenetic aging)
Maintaining high VO2 levels links to lower epigenetic age. (Exercise as a geroprotector: focusing on epigenetic aging)
The authors recommend focusing on VO2 in fitness programs. (Exercise as a geroprotector: focusing on epigenetic aging)
They also note strength matters but less than VO2. (Exercise as a geroprotector: focusing on epigenetic aging)
The review calls for testing causal CpG sites in clocks. (Exercise as a geroprotector: focusing on epigenetic aging)
It suggests DamAge and AdaptAge as examples. (Exercise as a geroprotector: focusing on epigenetic aging)
The authors ask whether exercise alters those causal sites. (Exercise as a geroprotector: focusing on epigenetic aging)
They say that would support a causal geroprotective effect. (Exercise as a geroprotector: focusing on epigenetic aging)
The review notes large individual variability in response. (Exercise as a geroprotector: focusing on epigenetic aging)
Those with higher baseline epigenetic age may benefit more. (Exercise as a geroprotector: focusing on epigenetic aging)
The authors urge precision exercise prescriptions. (Exercise as a geroprotector: focusing on epigenetic aging)
They call for trials that tailor programs to individuals. (Exercise as a geroprotector: focusing on epigenetic aging)
Now consider what this means for Thailand. (WHO Thailand physical activity profile 2022)
Thailand faces high sedentary time in parts of the population. (Physical activity, sedentary behaviour, and sleep in the Thai population 2023)
Surveys show mixed trends in adult activity after the pandemic. (Patterns and correlates of physical activity and sedentary behavior in Bangkok 2023)
WHO data reports insufficient physical activity in Thai adults. (WHO Thailand physical activity profile 2022)
Many Thai youth exceed recommended screen time. (Thailand 2022 report card on physical activity for children and youth)
High sedentary behavior may increase epigenetic aging risks. (Exercise as a geroprotector: focusing on epigenetic aging)
Thai public health programs already promote active lifestyles. (WHO Thailand physical activity profile 2022)
The new review gives more reason to scale up these programs. (Exercise as a geroprotector: focusing on epigenetic aging)
Community exercise could target older adults at risk. (Exercise as a geroprotector: focusing on epigenetic aging)
Temple-based group exercise may suit Thai culture. (Patterns and correlates of physical activity and sedentary behavior in Bangkok 2023)
Family-centered programs can boost adherence. (WHO Thailand physical activity profile 2022)
Public parks and active transport can increase daily VO2. (Physical activity, sedentary behaviour, and sleep in the Thai population 2023)
Workplace breaks can reduce sitting time. (Exercise as a geroprotector: focusing on epigenetic aging)
Schools can teach structured exercise habits early. (Thailand 2022 report card on physical activity for children and youth)
The review suggests broad societal gains from increased fitness. (Exercise as a geroprotector: focusing on epigenetic aging)
Lower biological age could reduce chronic disease burden. (Exercise as a geroprotector: focusing on epigenetic aging)
This result could ease pressure on hospitals and families. (WHO Thailand physical activity profile 2022)
The review also raises policy questions. (Exercise as a geroprotector: focusing on epigenetic aging)
Should Thailand target epigenetic age in public health metrics? (Exercise as a geroprotector: focusing on epigenetic aging)
Policymakers may need to fund long-term exercise trials. (Exercise as a geroprotector: focusing on epigenetic aging)
They may also need to measure fitness with VO2 testing more widely. (Exercise as a geroprotector: focusing on epigenetic aging)
Researchers in Thailand can test culturally tailored programs. (Patterns and correlates of physical activity and sedentary behavior in Bangkok 2023)
Such studies can measure epigenetic markers before and after training. (Exercise as a geroprotector: focusing on epigenetic aging)
Experts quoted the review in science press releases. (SciTechDaily summary)
The authors wrote, “Maintaining physical fitness delays epigenetic aging in multiple organs.” (Exercise as a geroprotector: focusing on epigenetic aging)
They added that exercise may act as a geroprotector. (Exercise as a geroprotector: focusing on epigenetic aging)
Independent commentators called for larger trials. (News-Medical coverage)
They urged testing in diverse populations. (Exercise as a geroprotector: focusing on epigenetic aging)
The review shows clear research directions. (Exercise as a geroprotector: focusing on epigenetic aging)
It sets priorities for standardization and mechanism studies. (Exercise as a geroprotector: focusing on epigenetic aging)
For clinicians, the message is practical. (Exercise as a geroprotector: focusing on epigenetic aging)
Encourage patients to add structured, moderate-to-vigorous exercise. (Exercise as a geroprotector: focusing on epigenetic aging)
Combine aerobic and resistance training for best results. (Exercise as a geroprotector: focusing on epigenetic aging)
Measure fitness improvements, not just weight loss. (Exercise as a geroprotector: focusing on epigenetic aging)
VO2 or step tests can track cardiorespiratory gains. (Exercise as a geroprotector: focusing on epigenetic aging)
For Thai workplaces, add active breaks and stair prompts. (WHO Thailand physical activity profile 2022)
For families, encourage daily shared walks or dance. (Thailand 2022 report card on physical activity for children and youth)
For schools, keep structured PE and fitness tests. (Thailand 2022 report card on physical activity for children and youth)
For local governments, invest in safe parks and bike lanes. (Physical activity, sedentary behaviour, and sleep in the Thai population 2023)
Temple and community centers can host group fitness. (Patterns and correlates of physical activity and sedentary behavior in Bangkok 2023)
Health insurers can reward fitness program participation. (WHO Thailand physical activity profile 2022)
Researchers should build trials that measure epigenetic clocks. (Exercise as a geroprotector: focusing on epigenetic aging)
Policy makers should fund long-term lifestyle studies. (Exercise as a geroprotector: focusing on epigenetic aging)
If exercise proves causal, healthspan benefits could rise. (Exercise as a geroprotector: focusing on epigenetic aging)
The science still needs larger and longer trials. (Exercise as a geroprotector: focusing on epigenetic aging)
Researchers must test various training types and doses. (Exercise as a geroprotector: focusing on epigenetic aging)
They must also study older and at-risk groups. (Exercise as a geroprotector: focusing on epigenetic aging)
The review opens a new angle on prevention in Thailand. (Exercise as a geroprotector: focusing on epigenetic aging)
It offers a science-backed reason to boost national fitness. (WHO Thailand physical activity profile 2022)
Actionable takeaway for Thai readers: start structured exercise now. (Exercise as a geroprotector: focusing on epigenetic aging)
Aim for moderate-to-vigorous aerobic activity plus strength twice weekly. (Exercise as a geroprotector: focusing on epigenetic aging)
Track fitness gains with simple step or step-test measures. (Exercise as a geroprotector: focusing on epigenetic aging)
Reduce prolonged sitting and add standing breaks every hour. (Exercise as a geroprotector: focusing on epigenetic aging)
Talk to a healthcare provider before starting intense programs. (Exercise as a geroprotector: focusing on epigenetic aging)
Health services can integrate fitness advice into routine care. (WHO Thailand physical activity profile 2022)
Community programs can tailor activities for older adults. (Patterns and correlates of physical activity and sedentary behavior in Bangkok 2023)
Researchers in Thailand can build trials on this review. (Exercise as a geroprotector: focusing on epigenetic aging)
This research may change how we view healthy aging. (Exercise as a geroprotector: focusing on epigenetic aging)
For now, exercise remains a low-cost way to protect future health. (Exercise as a geroprotector: focusing on epigenetic aging)