#Alzheimer

A new laboratory study from the University of California, Irvine, suggests that a simple pairing of natural compounds could rejuvenate aging brain cells and help clear harmful protein clumps linked to Alzheimer’s disease. The combo—nicotinamide, a form of vitamin B3, and epigallocatechin gallate (EGCG), the antioxidant found in green tea—restored energy levels in aging neurons and improved the cells’ ability to clear amyloid beta aggregates in dish-based experiments. While the research is early and conducted in cells, it adds to a growing global interest in metabolic approaches to brain health. For Thai readers, where families often shoulder caregiving duties for aging relatives and where green tea remains a culturally familiar beverage, the study offers a glimpse of potential future directions in nonpharmaceutical strategies to support cognitive well-being.

In Bangkok’s care centers and Thailand’s rural villages, a remarkable discovery is reshaping how families think about aging. Researchers from a leading U.S. university have identified a small group of people over eighty whose memories and thinking skills stay sharp—often rivaling those of people decades younger.

Lead with impact: the study shows that brain health can endure far longer than commonly believed, offering hope for Thailand’s rapidly aging population where more than 60 is the new 60, and dementia rates are rising. Data from international research underscores the value of understanding aging in a Thai context, where family networks and community ties play pivotal roles in daily life.

A decade-long study suggests that regular walking can meaningfully slow cognitive decline, especially for individuals with higher genetic risk for Alzheimer’s disease. Presented at the 2025 Alzheimer’s Association International Conference, the research followed nearly 3,000 adults aged 70 to 79. Participants who maintained or increased daily walking performed better on processing speed and executive tasks than those who were sedentary. The findings imply that small daily activity gains can matter for brain health.

A large international study suggests that a targeted mix of lifestyle changes can slow age-related brain decline. By combining a heart-healthy diet, regular aerobic exercise, mental stimulation, and increased social activity, older adults may maintain memory and thinking skills longer. The findings were shared at a major conference on Alzheimer’s disease and published in a leading medical journal, highlighting a promising path for Thailand’s aging population.

The POINTER study followed more than 2,100 sedentary adults in their 60s and 70s over two years. Participants who followed an intensive program—Mediterranean-style eating, frequent aerobic workouts, online cognitive training, structured social engagement, and close monitoring of blood pressure and blood sugar—achieved memory and cognition scores similar to peers up to two years younger. A senior investigator noted that these results demonstrate the possibility of influencing cognitive trajectories over time.

A new Harvard-led study offers a glimmer of hope in Alzheimer’s care. The researchers suggest that a rigorous, multi-faceted lifestyle program may slow, and in some cases partially reverse, cognitive decline in early-stage patients. While preliminary and not definitive, the results invite a rethinking of non-drug approaches to dementia, with potential relevance for Thailand’s aging population.

In a 20-week trial published in Alzheimer’s Research & Therapy, 51 participants with an average age around 73.5 were studied. The intervention group included 26 individuals who followed an intensive plan: a strict plant-based diet with home-delivered meals, daily aerobic and strength training, targeted supplements, mindfulness practices, and weekly group support via online sessions. This “everything-in-one” approach required about 12 hours of guided activities each week and was designed to be highly supportive, including involvement from participants and their spouses. The study’s intensity is notable, as most prior dementia research has tested far less demanding programs.

A major new study suggests that light exercise can help slow memory decline in seniors at risk for Alzheimer’s disease. The EXERT trial tracked nearly 300 sedentary older adults with amnestic mild cognitive impairment and found that both low-intensity activities—like stretching—and moderate-to-high intensity aerobic workouts helped keep cognitive function stable over 12 months. The findings appear in two papers in Alzheimer’s & Dementia and offer a practical path for families in Thailand facing an aging population.

A newly published study offers hope for millions of older adults at risk of Alzheimer’s disease, showing that even light forms of exercise may help slow cognitive decline. This large clinical trial, called the EXERT study, found that both low-intensity activities, such as stretching, and moderate-to-high intensity aerobic exercise kept cognitive function stable over a 12-month period for seniors with mild memory problems – a group considered high-risk for Alzheimer’s. The findings, reported in two papers in the journal Alzheimer’s & Dementia, could signal a practical path forward for Thai families concerned about brain health amid a rapidly aging population.

A new study in a leading scientific journal suggests the shingles vaccine may offer protection against dementia. The finding could influence health policy, elder care, and individual choices as Thailand’s population ages.

Dementia remains a major global health challenge, with cognitive decline affecting millions. As Thailand’s elderly population is set to grow, strategies to reduce dementia risk are increasingly important. The latest research indicates that a widely used vaccine could contribute to this effort.