#Alzheimersrisk

A major new study has found that spending prolonged hours seated each day may shrink the brain and raise the risk of cognitive decline, regardless of how much a person exercises. The findings, which have generated global attention, suggest that even regular physical activity may not be enough to counteract the potentially damaging effects of extended sedentary behavior on brain health, especially in older adults. For Thai readers, who increasingly balance desk-based work with daily commutes and digital leisure time, the message is clear: simply hitting the gym may not be enough—reducing sitting time itself is essential for healthy brain aging.

A groundbreaking study shows that long hours of sitting may cause brain shrinkage and faster cognitive decline, even for those who exercise regularly. For Thai readers juggling desk jobs, commutes, and digital leisure, the message is clear: cutting sitting time is crucial for healthy brain aging, not just hitting the gym.

Researchers tracked thousands of older adults over seven years, using MRI scans and genetic data to assess brain changes. They found that more daily sitting correlated with greater loss of brain volume and faster cognitive decline, even among people who met physical activity guidelines. The effect was stronger among individuals carrying the APOE-e4 gene, a known risk marker for Alzheimer’s disease, underscoring the importance of early lifestyle interventions for at-risk groups. Data from studies conducted by leading health organizations informs this insight, while health reporters around the world have highlighted the finding’s implications for aging populations.

A new study highlights the potential brain health risks of heavy drinking. Researchers report that consuming eight or more alcoholic drinks per week is associated with brain lesions called hyaline arteriolosclerosis, which reflect damaged blood vessels and reduced blood flow that can affect memory and thinking.

The findings also point to an increased presence of tau tangles, a biomarker connected to Alzheimer’s disease, among heavy drinkers and those with a history of heavy drinking. The research further suggests that former drinkers may have lower brain mass and poorer cognitive performance, while heavy drinkers showed a higher likelihood of earlier mortality compared with those who abstain.

In a concerning revelation for public health, recent research has established a link between heavy alcohol consumption and increased risk of brain lesions along with heightened odds of developing Alzheimer’s disease. According to a study published online in Neurology, consuming eight or more alcoholic drinks per week is associated with brain lesions known as hyaline arteriolosclerosis—indicative of damaged blood vessels that restrict blood flow, potentially impairing memory and cognitive abilities.