#Amygdala

A groundbreaking study has revealed that scents can fundamentally alter decision-making in mammals by forging indirect associations in the brain—findings that may pave the way for innovative treatments for mental health conditions in humans. The new research, conducted by a multidisciplinary team led by a doctoral student and supervised by a leading neuroscientist, used behavioral experiments in mice to explore how the brain’s response to smells influences future choices—offering important insights for both science and society.

A recent study reveals that odors can subtly shape decision-making by forming indirect brain connections. For Thai audiences, the findings illuminate potential future therapies for mental health conditions while underscoring the practical value of everyday scents.

In the research, mice learned to associate a banana scent with a pleasant taste and an almond scent with a salty taste. Later, the banana scent was paired with an unpleasant event. The mice began avoiding the sweet taste whenever the banana odor appeared, even though the taste itself did not change. This demonstrates that decisions can be guided by indirect connections between sensory cues. The lead investigator explains that the brain creates an indirect link between the sweet taste and the aversive experience through its association with a specific smell.

Researchers at a leading U.S. university have uncovered how dopamine, the brain’s reward signal, helps unlearn fear. The discovery, published in the Proceedings of the National Academy of Sciences, could transform treatments for anxiety and PTSD. For Thai readers, this points to new avenues for culturally sensitive therapies that emphasize safety and positive learning.

Across decades, scientists have known the amygdala drives both fear and its extinction. For Thais affected by traumatic events—natural disasters, traffic accidents, or the lingering impact of Covid-19—persistent anxiety and nightmares are common. The new insight into how the brain learns to feel safe offers hope for more effective, locally relevant therapies that reduce stigma around mental health.

Researchers at the Massachusetts Institute of Technology (MIT) have uncovered a crucial mechanism in the brain, revealing how dopamine—commonly known as the “feel-good” neurotransmitter—not only signals danger, but actively helps the brain unlearn fear. The findings, reported this week in the Proceedings of the National Academy of Sciences, could revolutionize potential treatments for anxiety disorders and post-traumatic stress disorder (PTSD), providing hope for millions worldwide—including those struggling in Thailand with trauma-related conditions (SciTechDaily).

In an intriguing development, scientists are uncovering the intricate workings of the brain that signal when we need to eat or drink. A recent study conducted by the Max Planck Institute for Biological Intelligence, in collaboration with the University of Regensburg and Stanford University, has found critical insights into how specific neurons within the brain’s amygdala may drive our basic urges to eat and drink. This discovery not only adds depth to our understanding of these essential functions but also opens new avenues for tackling conditions like obesity, anorexia, and even addiction.

A recent scientific discovery sheds light on how our brains signal when to eat or drink. Researchers from the Max Planck Institute for Biological Intelligence,Working with the University of Regensburg and Stanford University, have identified specific neurons in the amygdala that influence these basic urges. The findings could deepen our understanding of eating disorders, obesity, and addiction, while guiding better health strategies for Thailand’s growing health challenges.

In a study conducted with mice, researchers found distinct neuron groups within the amygdala that play separate roles in hunger and thirst. The amygdala is known for processing emotions and motivations, but this research highlights its involvement in core survival drives. According to senior researchers, manipulating particular neurons altered drinking behavior and pinpointed a neuron group linked to thirst regulation. Some neurons showed overlapping functions, affecting both thirst and hunger.