#Antihistamines

A widely used allergy medication, diphenhydramine—best known by the brand name Benadryl—is facing new scrutiny from health experts, who now argue that its risks outweigh its usefulness, particularly when safer alternatives are available. In a recent review published by leading allergy specialists from Johns Hopkins University and the University of California, San Diego, calls have intensified for this first-generation antihistamine to be pulled from over-the-counter (OTC) and prescription markets in the United States, igniting worldwide interest and concern, including in Thailand where similar medications are popular.

A recent University of Oregon study has raised important questions about the widespread use of antihistamines among active individuals, revealing that common medications for allergies could significantly impair recovery and muscle growth following endurance exercise. Published in the Journal of Applied Physiology, the research highlights a potential trade-off for Thai readers balancing allergy management with fitness goals, as these medications may hinder the very process the body relies on to heal and adapt from exercise-induced stress (KLCC).

A recent headline in international media warns that a common over-the-counter (OTC) medication, widely used for allergies, may increase the risk of dementia, prompting concern among health professionals and the public in Thailand and globally. Leading doctors cited in a recent report from Women’s Health Magazine are drawing attention to mounting research that connects the use of certain antihistamines—medicines typically purchased without a prescription—to a greater likelihood of future cognitive decline.