#Antihistamines

A widely used allergy medication, diphenhydramine—best known by the brand name Benadryl—is facing new scrutiny from health experts, who now argue that its risks outweigh its usefulness, particularly when safer alternatives are available. In a recent review published by leading allergy specialists from Johns Hopkins University and the University of California, San Diego, calls have intensified for this first-generation antihistamine to be pulled from over-the-counter (OTC) and prescription markets in the United States, igniting worldwide interest and concern, including in Thailand where similar medications are popular.

A University of Oregon study raises important questions about antihistamines and how they affect recovery and muscle gains after endurance exercise. Published in the Journal of Applied Physiology, the research suggests a trade-off between allergy relief and athletic adaptation. For Thai readers, it invites a closer look at how allergy medications might influence fitness goals amid Thailand’s active outdoor culture.

In Thailand, allergy relief is vital during peak dust and pollen seasons in Bangkok and agricultural periods. Many people rely on antihistamines to ease symptoms like runny noses and itchy eyes. The latest findings add nuance to this reliance, indicating that higher-dose antihistamines could interfere with the body’s natural recovery after intense training. As outdoor activities grow in popularity—from cycling routes near historic sites to community runs around urban parks—understanding how medications interact with training becomes increasingly relevant.

A recent University of Oregon study has raised important questions about the widespread use of antihistamines among active individuals, revealing that common medications for allergies could significantly impair recovery and muscle growth following endurance exercise. Published in the Journal of Applied Physiology, the research highlights a potential trade-off for Thai readers balancing allergy management with fitness goals, as these medications may hinder the very process the body relies on to heal and adapt from exercise-induced stress (KLCC).

A recent headline in international media warns that a common over-the-counter (OTC) medication, widely used for allergies, may increase the risk of dementia, prompting concern among health professionals and the public in Thailand and globally. Leading doctors cited in a recent report from Women’s Health Magazine are drawing attention to mounting research that connects the use of certain antihistamines—medicines typically purchased without a prescription—to a greater likelihood of future cognitive decline.

Recent international coverage highlights a potential link between certain over-the-counter antihistamines and an increased risk of cognitive decline. Leading physicians note that long-term or heavy use of first-generation antihistamines—commonly found in allergy and cold remedies—may contribute to future dementia, especially among older adults. This aligns with a growing body of evidence suggesting anticholinergic medications can affect memory and learning.

Antihistamines are a staple in Thai households, particularly as urban pollution and allergy rates rise in Bangkok and other cities. The caution matters for millions who self-medicate with OTC drugs, often without professional guidance. Thai readers should understand which medicines carry higher cognitive risks and how to choose safer options.