#Autismresearch

Thailand, like many countries worldwide, is witnessing increased public concern as reported cases of autism rise steeply each year. However, recent research and leading international experts contend that this apparent surge in autism diagnoses may not reflect a true rise in the prevalence of autism itself, but rather the product of social, medical, and diagnostic transformations over recent decades (BBC).

The significance of understanding these trends cannot be understated for Thai parents, educators, and healthcare professionals. Against a backdrop of growing public discussion and sometimes anxiety over neurodevelopmental disorders, clear and accurate information about autism spectrum disorder (ASD)—its causes, diagnosis, and support—remains critical for societal awareness, policy planning, and resource allocation.

Public concern about autism is rising in Thailand as diagnoses increase each year. Experts say the uptick is not necessarily a true increase in autism itself, but the result of social, medical, and diagnostic changes over the past decades. Research from international institutions suggests that greater awareness, improved screening, and evolving criteria are driving more children into diagnosis.

Understanding these trends is essential for Thai parents, teachers, and healthcare professionals. Clear, accurate information about autism spectrum disorder (ASD)—its causes, diagnosis, and support—helps with policy planning, resource allocation, and reducing anxiety around neurodevelopmental differences.

Recent groundbreaking research from UCLA Health reveals that puberty triggers significant changes in brain connectivity, which may help explain why some children with chromosome 22q11.2 deletion syndrome, a rare genetic disorder, are at an increased risk for developing neuropsychiatric conditions like autism and schizophrenia. The findings, published in Science Advances, provide new insights into the biological mechanisms underlying these complex conditions, offering hope for future interventions.

Chromosome 22q11.2 deletion syndrome is caused by missing DNA on chromosome 22 and is known to be associated with a higher risk of autism and schizophrenia. Researchers from both UCLA and the Italian Institute of Technology utilized functional brain imaging on both humans and genetically modified mice to explore how this genetic anomaly affects neurodevelopment. They observed that certain brain regions involved in social skills and autism were hyperconnected before puberty and shifted to being under-connected post-puberty. These changes were linked to synaptic activity, with significant implications for affected individuals.

A new study from UCLA Health shows that puberty can reshape brain connectivity in children with chromosome 22q11.2 deletion syndrome, a rare genetic condition. The changes may help explain why these children have a higher risk of neuropsychiatric conditions such as autism and schizophrenia. The researchers published their findings in Science Advances, offering fresh insight into the biology behind these disorders and potential avenues for future interventions.

Chromosome 22q11.2 deletion syndrome arises from missing DNA on chromosome 22 and is linked to increased risks for autism and schizophrenia. Researchers from UCLA and the Italian Institute of Technology used functional brain imaging in both humans and genetically modified mice to explore how this genetic anomaly affects brain development. They found that networks involved in social processing were overconnected before puberty and became underconnected after puberty, with synaptic activity playing a central role in these changes.