Scientists Confirm 67-Year-Old Theory on Vitamin B1’s Role, Opening New Doors for Green Chemistry
In a historic breakthrough, scientists have finally confirmed a 67-year-old hypothesis about vitamin B1, also known as thiamine, radically advancing our understanding of how this crucial vitamin works in the human body. This finding not only settles a decades-old scientific debate but also unlocks new possibilities for eco-friendly chemical production, with potential impact reaching far beyond the laboratory.
The story of this discovery begins in 1958, when a chemist from Columbia University theorized that vitamin B1 might perform its vital metabolic functions through the formation of an elusive molecular structure called a carbene. Carbenes are notoriously unstable and tend to decompose instantly in aqueous (water-based) environments like the human body, making the hypothesis seem improbable for more than half a century. For years, the idea was dismissed as “crazy,” as quoted by Vincent Lavallo, a chemist at the University of California, Riverside, who led the recent research that validated this bold proposal.