#Betaine

A natural compound found in common foods and produced by the kidneys during endurance exercise may unlock the anti-aging benefits of regular physical activity—without any need to hit the gym, according to a landmark study published in the journal Cell by a Chinese Academy of Sciences research team. The discovery could pave the way for “exercise-in-a-pill” therapies that offer hope to Thailand’s rapidly aging population and to those with limited mobility or chronic health issues.

In a landmark study that could reshape approaches to healthy ageing, researchers have identified a natural supplement, betaine, that mimics the benefits of exercise—including reduced inflammation and slowed tissue ageing. This finding, recently published in the scientific journal Cell and widely reported in international media, has the potential to revolutionize the fight against age-related diseases and extend human healthspan, particularly for those unable to maintain regular physical activity (gbnews.com, medicalxpress.com, pubmed.ncbi.nlm.nih.gov, nmn.com).

A collaborative team from the Chinese Academy of Sciences and Capital Medical University in Beijing conducted an in-depth analysis revealing that betaine, a compound found naturally in foods such as beetroot, spinach, and whole grains, interacts with key molecular pathways involved in inflammation and cellular ageing. Crucially, regular exercise was found to increase levels of betaine in the body—but new evidence now shows that taking betaine as a supplement can trigger similar anti-ageing effects, offering hope to those unable to exercise regularly due to physical limitations or chronic illness.

A groundbreaking study by Chinese researchers has finally shed light on the deeper mechanisms behind how long-term exercise slows ageing, pinpointing a naturally occurring compound called betaine as a critical player in the process. This research, published in the journal Cell in late June 2025, offers not just a better scientific understanding but also raises exciting possibilities for new anti-ageing interventions—even for those who have difficulty exercising due to age or health challenges (SCMP; PubMed; Nature).