#Cbd

A new study reported in Neuropharmacology suggests that cannabidiol, the non-intoxicating compound found in cannabis, may buffer against some lasting psychological and brain changes produced by social stress in adolescence. In a pair of carefully designed experiments, researchers found that giving CBD to male mice before repeated social defeats reduced social avoidance and the heightened readiness to seek drugs like cocaine that often follows stress exposure. The work also showed CBD reversed several stress-induced shifts in brain gene expression tied to the serotonin system, the endocannabinoid system, and the body’s main stress axis, the hypothalamic-pituitary-adrenal axis. Importantly, the effects depended on the dose, and the study used animal models, so translating these findings to humans will require cautious, rigorous clinical testing.

A Brazilian study suggests cannabidiol (CBD) may help ease autism symptoms in children and young adults. Researchers from the University of São Paulo reported that oral CBD led to improvements in social skills, fewer tantrums, and reduced aggression in participants. Presented at the 2025 European Congress of Psychiatry, the findings indicate CBD could complement traditional therapies, though experts urge larger trials to confirm results.

Interest in CBD arises from its role in supporting the body’s endocannabinoid system, which influences mood and stress. Unlike THC, CBD does not cause a high, making it a more acceptable option for neurological conditions beyond autism, such as epilepsy, while avoiding psychoactive effects.

In an exciting development, a Brazilian study has highlighted cannabidiol (CBD) as a potential supplement in easing autism symptoms in children and young adults. Researchers from the University of São Paulo have found that oral CBD intake led to significant improvements in social skills, reduced aggression, and eased tantrums among young participants. This promising research, presented at the 2025 European Congress of Psychiatry, suggests that CBD could be incorporated into autism treatment plans alongside traditional therapies. However, experts remain cautious, calling for larger trials to confirm these findings.