#Claustrum

A joint team of Chinese and French researchers has produced the most detailed map yet of the claustrum, a thin brain region long shrouded in mystery. The study in Cell, published on April 3, uses single-cell spatial transcriptomics to chart the claustrum in the crab-eating macaque and reveals its complex connections with the cortex and hippocampus. The researchers highlight evolutionary differences between primates and rodents, suggesting that brain evolution may shape consciousness. According to the study, this atlas provides a molecular framework for exploring how the claustrum contributes to cognition and awareness.

A team of Chinese and French researchers has produced the most detailed blueprint yet of the mysterious claustrum region in primate brains, a scientific advance that could help unravel the biological roots of consciousness and reframe our understanding of mental health and awareness. Published in the prestigious journal “Cell”, the April 3 study charts the intricate landscape of the crab-eating macaque’s claustrum—a tiny strip of tissue in the brain historically overshadowed by more prominent regions, but now emerging as a prime suspect in the quest to decode the essence of conscious experience (source).

A joint team of Chinese and French researchers has produced an unprecedented map of the claustrum, a brain region long thought to coordinate conscious experience, in the crab-eating macaque. Published in Cell in April 2025, the study delivers a single-cell spatial transcriptome atlas and a whole-brain connectivity map, offering a detailed view of cellular diversity and neural wiring that underpins awareness in primates. The research provides a blueprint of the claustrum and advances our understanding of how consciousness may emerge from brain circuits. This progress resonates with Thailand’s growing interest in neuroscience and mental health.

In a landmark advance that could reshape how science understands consciousness, a collaboration of Chinese and French researchers has meticulously mapped the claustrum—the brain region often dubbed as a “conductor of consciousness”—in the crab-eating macaque monkey. Reporting their findings in the highly respected journal Cell in April 2025, the team unveiled an unprecedented single-cell spatial transcriptome atlas and a whole-brain connectivity map, shedding new light on the neural diversity and complex wiring that underpins conscious awareness in primates Cell, SCMP. This research not only offers a detailed blueprint of the elusive claustrum, but also marks a major step toward identifying how consciousness itself emerges from brain circuits—a quest with deep philosophical and practical significance for humanity, including Thai society.