#Clinicaltrials

Ginseng, the Panax root often hailed as the “root of life,” sits at a crossroads of tradition and science. For centuries, it has held a storied place in East Asian healing, revered in royal courts, forests, and markets. Today, researchers and health enthusiasts alike examine its potential within modern medicine, aiming to balance respect for traditional use with rigorous evidence.

In East Asia, ginseng has long signified vitality. Archaeological and historical records reveal its presence in China for thousands of years, where the root’s human-like shape gave it symbolic meaning as a source of life and strength. Classic texts describe ginseng as a superior tonic for a wide range of ailments and for recovery, with traditional Chinese medicine attributing its effects to reinforcing Qi, and balancing internal elements like yin and yang. Contemporary summaries of these concepts frame ginseng as an adaptogen, a term now popular in Western discussions of stress resilience and energy.

For centuries, Panax ginseng—better known simply as ginseng—has held legendary status in Asian herbal traditions, earning names such as “root of life” and “herb for all ills.” Its storied past is woven through the royal courts of China, the mountain forests of Korea, and the bustling international herbal markets of Japan, before ultimately spreading around the globe. Today, ginseng sits at a fascinating intersection: still revered in traditional practices, yet increasingly scrutinized and celebrated by modern medicine. As both scientists and health enthusiasts revisit this ancient remedy, a compelling portrait emerges—one that blends ancient healing wisdom with contemporary clinical evidence, and urges a thoughtful, respectful approach to its use.

A recent study in the Journal of Psychedelic Studies sheds light on the lingering psychological challenges some people experience after psychedelic experiences and what helps most. The research highlights that while anxiety and panic attacks can be disruptive, existential struggles and reduced self-esteem often persist for more than a year.

As global interest in psychedelic-assisted therapy grows, these findings are timely for health professionals and the public, including those in Thailand where discussions about alternative mental health treatments are expanding. Prior work has shown that a portion of users—estimates range from 5% to 25%—continue to deal with psychological effects long after their initial experience. Understanding these risks is essential for Thai healthcare providers and communities.

A groundbreaking new study published this week in the Journal of Psychedelic Studies offers one of the clearest views yet into the lingering psychological challenges some individuals face after using psychedelic drugs like psilocybin, LSD, and ayahuasca—and what helps them cope. Researchers found that while anxiety and panic attacks are among the most disruptive post-experience effects, difficulties such as existential struggles and reduced self-esteem often last for more than a year, underscoring the need for better support systems.

A wave of optimism is sweeping Thai families affected by Parkinson’s disease as the FDA approves XS-411 for Phase 1 trials in the United States. Developed by a biotech firm, the therapy uses induced pluripotent stem cells (iPSCs) to generate dopamine-producing neurons lost to the disease. If safe and effective, this approach could reshape how neurodegenerative conditions are treated and accelerate regenerative medicine worldwide, with potential implications for Thailand as global research progresses.

Thai patients and their families living with Parkinson’s disease received hopeful news this week after the US Food and Drug Administration (FDA) approved a first-of-its-kind stem cell therapy, XS-411, for Phase 1 clinical trials in the United States. Developed by biotech firm Xellsmart, this innovative therapy harnesses induced pluripotent stem cells (iPSCs) to regenerate the healthy, dopamine-producing neurons lost in patients with Parkinson’s. This marks a milestone in neurodegenerative disease treatment and offers a look toward the future of regenerative medicine, not only in the US but potentially in Thailand as global clinical research expands (Parkinson’s News Today).

Two new clinical studies strengthen the case for stem cell transplants as a potential treatment for Parkinson’s disease. Published in Nature, the trials show that surgically implanted, lab-grown dopamine-producing cells can improve symptoms with no serious early side effects. This marks a meaningful milestone after decades of research aimed at replacing the neurons that gradually fail in Parkinson’s.

Parkinson’s disease damages dopamine-producing neurons in the brain, leading to tremors, rigidity, fatigue, and slowing of movement. While medications and deep brain stimulation help manage symptoms, there is no cure yet. In Thailand, an aging population is increasing the burden of neurological illnesses, underscoring the need for new, accessible therapies and clear regulatory pathways.

Exciting news in the fight against Parkinson’s disease: Two newly published clinical studies are providing the strongest evidence yet that stem cell transplants may offer a powerful new treatment for people living with this debilitating condition. In results published this week in the journal Nature, both research teams found that surgically implanting lab-grown dopamine-producing cells into the brains of patients led to symptom improvements and no serious side effects—marking an important milestone after decades of painstaking efforts to replace the dying neurons at the root of Parkinson’s. For over a million Americans and countless others worldwide, including an estimated 150,000 Thais suffering from Parkinson’s, this research signals fresh hope for dramatically improving quality of life in the coming years (NPR).

Cyperus rotundus, known in Thai as แห้วหมู (also หญ้าแห้วหมู or หัวแห้วหมู), has for generations stood in Thai herbal cabinets and village gardens. This unassuming sedge, prized for its tubers, embodies resilience and healing. Today, scientists are rediscovering its potential, linking ancestral wisdom with contemporary research. As Thai daily life faces stress and chronic conditions, readers seek remedies that blend tradition with evidence.

In Thailand’s rural heartlands from Mae Hong Son to the south, the plant’s nut-shaped tubers have long been used in home remedies. Thai traditional healers have employed แห้วหมู for digestive issues, menstrual discomfort, fever, and mood regulation. Similar systems—Ayurveda, Traditional Chinese Medicine, and Islamic Tibb—also recognize the herb under names such as Musta, Xiang Fu, and Nutgrass. In Thai practice, แห้วหมู features in formulas for longevity, women’s health, and digestive wellness, with roots in medical texts and temple paintings.

For centuries, the humble แห้วหมู (Cyperus rotundus L.)—also known as หญ้าแห้วหมู or หัวแห้วหมู in various parts of Thailand—has held an esteemed place in traditional Thai herbal medicine cabinets and village gardens. Revered across Asia and beyond for its underground tubers, this unassuming sedge has been a symbol of resilience and healing. Today, a wave of renewed scientific interest is validating aspects of its age-old uses, connecting ancestral knowledge with the rigors of modern clinical research. With daily lives increasingly marked by stress, chronic conditions, and lifestyle diseases, Thai readers are seeking both hope and evidence in remedies that endure from the past.

Red Kwao Krua, known to botanists as Butea superba Roxb., is a remarkable herbal remedy that has woven itself into the tapestry of Thai traditional medicine for centuries. Harvested from the tuberous roots of a robust climbing legume native to Southeast Asia, this “herbal hero” carries with it a blend of cultural reverence, folklore, and—thanks to contemporary research—burgeoning scientific interest. In a health-curious era when Thais and global audiences alike seek a synthesis of traditional wisdom and biomedical validation, Red Kwao Krua emerges as an emblematic plant deserving of closer attention.

Red Kwao Krua, known scientifically as Butea superba Roxb., has long anchored Thai traditional medicine. The tuberous roots of this robust climbing legume are revered in villages and royal courts alike, now attracting modern scientific interest. In an era hungry for evidence-based wellness, Red Kwao Krua embodies the conversation between age-old wisdom and contemporary research.

Across Thailand, Red Kwao Krua’s story begins in traditional apothecaries and extends into university laboratories. Folk healers have long used its root powders, decoctions, and tinctures to support vitality and stamina. In Thai, the plant is called กวาวเครือแดง, with regional names such as จานเครือ and จอมทอง. Roots are often prepared by infusion in water or alcohol or blended into polyherbal formulations.