#Connectome

An international team of more than 150 scientists has created the most detailed map to date of how visual information travels through the brain. The study uncovers hundreds of millions of connections within a single grain-sized sample of mouse brain tissue and brings researchers closer to understanding sight. Published in Nature on April 9, 2025, the project combines genetic engineering, high-resolution electron microscopy, and deep learning to chart both the physical wiring and the neurons’ real-time responses to visual stimuli. The result is a 1.6-petabyte dataset—a scale comparable to 22 years of continuous high-definition video—capturing a microscopic brain fragment in extraordinary detail.

A groundbreaking international study led by over 150 scientists has produced the most detailed map ever of how visual information moves through the brain, uncovering more than 500 million intricate connections within a speck of mouse brain tissue and bringing the world closer to understanding how we see. Published in the journal Nature on April 9, 2025, the research combines genetic engineering, high-powered electron microscopy, and deep learning to capture not only the physical wiring of over 200,000 brain cells but also their real-time electrical activity in response to visual stimuli. The project—hailed as one of the most complex neuroscience experiments ever attempted—has generated a dataset of unprecedented size and detail: 1.6 petabytes, about the equivalent of 22 years of continuous high-definition video, all representing a single grain-sized fragment of brain.

An international team has produced the first detailed three-dimensional map of a mammal’s brain, revealing unprecedented insight into brain structure and function. Focusing on a tiny fragment of a mouse’s visual cortex, the achievement marks a milestone for neuroscience with potential to improve diagnosis and treatment of brain diseases such as Alzheimer’s and autism. For Thai readers, the findings underscore how advances in brain science can influence medicine, education, and future AI applications amid Thailand’s aging society.

In a scientific breakthrough once thought impossible, an international team of researchers has created the first detailed three-dimensional map of a mammal’s brain, offering an unprecedented window into the structure and function of the mind. This ambitious feat, achieved by studying a tiny fragment of a mouse’s visual cortex, marks a pivotal advance in neuroscience and holds profound implications for understanding brain diseases such as Alzheimer’s and autism (CNN/Yahoo! News).

A global team of researchers has unveiled the most detailed three‑dimensional map of a mammalian brain to date. Using a tiny mouse brain fragment the size of a grain of sand, scientists at the Allen Institute for Brain Science, Baylor College of Medicine, and Princeton University mapped 84,000 neurons and more than 500 million synapses in a single cubic millimeter. The digital reconstruction, published in Nature, is described as the most comprehensive mammalian brain map yet and is advancing the search for treatments for brain disorders such as Alzheimer’s, Parkinson’s, autism, and schizophrenia. Research by leading institutions shows the potential impact for future Thai medical science and patient care.

In a scientific feat once thought to border on the impossible, a global team of researchers has produced the first-ever hyper-detailed, three-dimensional map of a mammalian brain, marking a significant leap forward in neuroscience. Using just a tiny speck of mouse brain matter—the size of a grain of sand—scientists at the Allen Institute for Brain Science, Baylor College of Medicine, and Princeton University meticulously mapped out the intricate web of 84,000 neurons and over 500 million synapses within a cubic millimeter of tissue. This digital reconstruction, now published in the journal Nature, is being hailed as the most comprehensive mammalian brain map ever generated, fueling optimism for breakthroughs in understanding brain disorders such as Alzheimer’s, Parkinson’s, autism, and schizophrenia (CNN).