#Cosmeceuticals

Known by many names across the region—กระแจะ, พญายา, ขะแจะ, ตุมตัง, and others—Hesperethusa crenulata is a tree whose bark, stem, and wood have long been treasured in traditional Southeast Asian medicine. In Thailand, the engraved word “กระแจะ” conjures centuries of healing practices, folk wisdom, and even romance, as this herbal ingredient not only soothes physical ailments but is often mentioned in the poetry and cultural traditions of the central plains, the north, and northeast. Today, กระแจะ’s ancient legacy is finding new life as research teams shine the spotlight on its potent phytochemicals and their promising applications for beauty, health, and disease prevention.