#Dementia Research

A groundbreaking blood test has been developed to aid in the diagnosis and management of Alzheimer’s disease, providing hope for those experiencing cognitive decline. This innovation enables doctors to determine the presence and progression of Alzheimer’s, offering a significant leap forward in personalizing patient care. The test can potentially identify suitable drug therapies earlier in the disease’s progression, making treatments like donanemab and lecanemab more effective, as these are beneficial primarily in early-stage Alzheimer’s.

A groundbreaking study from the University of Chicago has turned conventional wisdom on memory formation on its head, offering new insights that could have profound implications for understanding neurological disorders such as dementia—an area of keen interest for Thai researchers and healthcare professionals. The study, published in the prestigious journal Nature Neuroscience, dissects the intricate workings of synaptic plasticity, revealing complex mechanisms that depart from traditional theories. Synaptic plasticity, previously understood through the lens of Hebbian principles—where neurons that frequently activate together tend to reinforce their connections—now invites a new paradigm: Behavioral Timescale Synaptic Plasticity (BTSP).