#Dendrites

A major study from Ohio State University reveals why memories formed close in time often feel linked. Published in Nature Neuroscience, the research shows dendrites—tiny branches on neurons—play an active role in binding memories. For Thai readers, the findings shed light on daily life and potential approaches to treating memory disorders such as Alzheimer’s disease.

Memories can blend into a continuous story, especially when events occur near each other in time. Scientists observed mice in real time using advanced imaging tools, including miniaturized microscopes. The study focused on the retrosplenial cortex, a brain region crucial for spatial and contextual memory, and showed that dendrites actively participate in memory formation, not just receive information.

A groundbreaking study from The Ohio State University unveils why memories occurring close in time often feel connected, extending our understanding of memory beyond the traditional confines of the main brain cells. Published in the esteemed journal Nature Neuroscience, this research highlights the pivotal role of dendrites—fine branches protruding from neurons—in binding memories together. For Thai readers, this insight offers both a deeper understanding of how we experience our daily lives and potential implications for treating memory disorders such as Alzheimer’s disease.

A groundbreaking study from Ohio State University, published in Nature Neuroscience, shows that memories formed close in time may be stored in dendrites—the branches of neurons—rather than in cell bodies. This finding explains why events on the same day often feel linked and could guide future therapies for memory-related disorders.

Led by Megha Sehgal, the researchers used advanced imaging in mice to demonstrate that the same dendritic branches activate when experiences are encoded in quick succession. The dendritic linkage occurs in the retrosplenial cortex, a brain region integral to contextual memory. The work reveals that memories can be bound together through localized changes in dendritic segments, offering a new lens on how the brain connects related experiences.

A groundbreaking study has unveiled how our brains physically associate memories formed close in time, offering intriguing insights that could impact the understanding of memory-related disorders. Conducted at Ohio State University and recently published in Nature Neuroscience, the research highlights that rather than being encoded in the cell bodies of neurons, memories formed within short timeframes are stored in the dendrites, which are intricate extensions of neurons.

This discovery is significant as it elucidates why events occurring on the same day often feel inherently linked, in contrast to those spaced out over weeks. Dendrites, long overshadowed by the neuron cell bodies in memory studies, are now recognized as playing a crucial role in memory linkage. The researchers, led by Megha Sehgal, utilized advanced imaging techniques on mice, which revealed that the same dendritic branches get activated when closely timed experiences are encoded, thereby binding the memories together.