#Depression

Exercise has long been known as a natural mood booster, but a new study sheds light on just how impactful walking can be in the battle against depression. Published in JAMA Network Open, this research reveals that walking more than 5,000 steps per day is linked with a noticeable reduction in depression symptoms among adults. This analysis, which encompasses 33 separate studies involving over 96,000 participants, reinforces the important role that physical activity plays in mental health.

With the spotlight often focused on anxiety attacks, many might overlook the equally impactful but lesser-known “depression attack.” Highlighted recently by HuffPost’s report, this continues to be a growing concern in mental health discussions. Unlike the clinical diagnosis of major depressive disorder (MDD), depression attacks describe a sudden, intense wave of despair and emotional paralysis, as explained by clinical psychologist Comfort Shields, indicating an immediate need for awareness and understanding.

In Thailand, where mental health often intertwines deeply with cultural taboos and socioeconomic challenges, understanding this phenomenon can empower individuals to seek support and acknowledge their mental wellbeing. While depression attacks aren’t clinically diagnosed, they manifest through sharp “attacks” of severe sadness and feelings of helplessness, unlike the prolonged nature of MDD. Monica Amorosi, a licensed mental health counselor, suggests these attacks may seem sudden but are often the result of intensified symptoms due to various triggers.

In recent scientific developments, night owls—people who naturally stay up late—have been found to have an elevated risk of depression compared to their early-rising counterparts. According to a study published in March 2025, factors such as sleep quality, mindfulness practices, and lifestyle choices play significant roles in this increased risk. This emerging research holds particular relevance for Thailand, where the impact of urban lifestyles and technological engagement contributes to shifting sleep patterns.

In a groundbreaking study conducted by researchers at King’s College London, a brain pathway known as the kynurenine pathway is being explored for its potential role in the higher rates of depression observed in teenage girls compared to boys. As reported by Medical Xpress, this study is pivotal in understanding the underlying biological factors that contribute to depression, which affects approximately 280 million people globally.

The significance of this study lies in its focus on adolescence—a developmental stage marked by significant neurological and psychological changes. The research examines how the kynurenine pathway, which processes the amino acid tryptophan into either neuroprotective or neurotoxic chemicals, differs in its operation between male and female adolescents. This research is particularly poignant for Thai adolescents, as mental health awareness grows within the country amidst shifting cultural norms and increasing academic pressures.