#Depression

A provocative study from Iran suggests that depression and anxiety may spread between romantic partners beyond shared circumstances. The research points to the exchange of mouth bacteria during intimate moments like kissing as a potential pathway. The findings, published in Exploratory Research and Hypothesis in Medicine, have sparking discussions about how mood can be influenced within intimate relationships.

Why this matters for Thai readers: Mental health is a growing priority in Thailand, with rising rates of depression across age groups. Understanding how relationships and daily habits impact well-being could inform more holistic approaches to care. Thai families often share close daily routines and meals, making the concept of mutual influence particularly relevant.

A wave of new research offers hope for people in Thailand and around the world who live with depression and post-traumatic stress disorder. Targeted cognitive training may reduce negative self-perceptions, a core symptom of these conditions, potentially improving mental health outcomes and quality of life.

In Thailand, the study’s relevance is clear. Cultural values around face, self-respect, and resilience shape how people experience mental illness. Negative self-beliefs can worsen symptoms, hinder daily functioning, strain families, and limit social and career opportunities—issues that matter deeply in a Thai context that emphasizes harmony and personal presentation.

A newly published study by University College London (UCL) researchers reveals that individuals who have taken antidepressants for more than two years are vastly more likely to suffer severe and long-lasting withdrawal symptoms when discontinuing the medication, compared to those prescribed antidepressants for less than six months. The findings, which come at a critical time as antidepressant prescriptions have soared worldwide, suggest that the duration of use is a key driver for withdrawal difficulty, potentially prompting a significant shift in how these medications are prescribed and managed both globally and in Thailand.

Recent findings from University College London show that people on antidepressants for more than two years are far more likely to experience severe and lasting withdrawal when stopping the medication than those who used them for under six months. With antidepressant prescriptions rising worldwide, the study suggests the duration of use strongly drives withdrawal difficulty and could influence prescribing and tapering practices in Thailand.

In Thailand, antidepressants such as SSRIs are commonly prescribed for depression and anxiety, reflecting international trends. Data from the UCL study indicate that long-term users have a tenfold higher risk of withdrawal compared with short-term users, and about one in four people who have taken antidepressants for more than two years report severe withdrawal symptoms. The growing acceptance of mental health treatment in Thai communities after the pandemic makes these findings highly relevant for patients and clinicians.

A new wave of research offers hope for individuals in Thailand and worldwide battling depression and post-traumatic stress disorder (PTSD), as cognitive training techniques show promise in reducing negative self-perceptions—a hallmark symptom of these mental health conditions. According to a recent report by PsyPost, targeted cognitive training interventions could reshape the way people with depression and PTSD view themselves, potentially supporting better mental health outcomes and overall quality of life.

For Thai readers, this research is particularly significant given the culture’s deep-rooted values around face, self-respect, and the importance placed on emotional resilience. Negative self-perceptions not only exacerbate mental health conditions but can also impede daily functioning, strain family relationships, and limit social and career opportunities—issues especially salient in the Thai context, where societal harmony and personal presentation are emphasized.

A major new study from researchers at the University of California, San Francisco (UCSF) has found a significant association between increased social media use and rising depression rates among young adolescents—a finding that is especially relevant as Thai families grapple with the impact of digital technology on youth mental health. The research, published this week and covered by KQED, tracked nearly 12,000 children and adolescents nationwide over several years and revealed that their social media usage rose sharply between the ages of 9 and 13, paralleled by a concerning 30% uptick in reported depressive symptoms during the same period.

A major study from researchers at the University of California, San Francisco (UCSF) finds a significant link between growing social media use and rising depression among young adolescents. The findings are highly relevant for Thai families navigating the impact of digital technology on youth mental health. The research followed nearly 12,000 children and teenagers over several years and showed sharp increases in social media use between ages 9 and 13, coinciding with a 30% rise in reported depressive symptoms.

A new study points to mindfulness-based cognitive therapy (MBCT) as a practical, affordable option for people whose depression persists after standard care. This finding has important implications for strengthening Thailand’s mental health services and support networks. The research highlights how MBCT can fill the “missing middle”—patients who are not well enough for intensive specialist care but still need more than basic treatment.

Depression remains a heavy burden for many individuals and their families in Thailand. About 30% continue to experience daily symptoms such as low mood, fatigue, and hopelessness despite therapy and medication. The impact extends to workplaces, communities, and the broader economy, where lost productivity and higher health costs are felt nationwide. Data from Thailand’s public health landscape show that depression is a leading contributor to disability and socioeconomic strain in the country.

A promising new study has shed light on mindfulness-based cognitive therapy (MBCT) as an effective, affordable treatment for people whose depression persists despite standard care, with implications for improving support strategies in Thailand’s mental health services. The research, recently highlighted by The Conversation, found that MBCT could fill a crucial gap for the so-called “missing middle”—patients left behind after common therapy and medication fail to fully relieve their symptoms.

Around 30% of people living with depression face an unyielding daily struggle: even after therapy and medication, the fog of low mood, fatigue, and hopelessness lingers. This phenomenon not only takes a toll on individuals, but also affects Thai families, workplaces, and the broader economy, echoing trends observed globally. Depression, already a leading cause of disability in Thailand, imposes significant direct and indirect costs on society, including lost productivity and higher health care expenditures (WHO Thailand).

A new study highlights mindfulness-based cognitive therapy (MBCT) as a promising option for people who do not fully recover after standard depression treatment. This approach could offer renewed hope for those with lingering depressive symptoms, a challenge that affects up to 30% of individuals with depression worldwide, including many in Thailand.

Depression remains a leading cause of disability globally and in Thailand, where health authorities report millions affected each year. While antidepressants and talking therapies work for many, some patients never fully escape the fog of low mood and exhaustion after treatment. In an English study published in The Conversation, researchers estimate that about one in three people with depression still struggle with symptoms even after completing therapy and medication.

A recent study has shed light on the potential of mindfulness-based cognitive therapy (MBCT) to address a persistent gap in depression care—helping individuals who do not fully recover after standard treatment. This promising approach could offer renewed hope for those living with lingering depressive symptoms, a scenario that affects up to 30% of people diagnosed with depression worldwide, including many in Thailand.

Depression remains a leading cause of disability both globally and in Thailand, where the World Health Organization estimates over 1.5 million Thais suffer from the condition each year (WHO). While effective antidepressants and talking therapies exist, for many patients the journey out of depression is not straightforward. As outlined in a new study conducted in England and published in The Conversation (The Conversation), about one-third of people with depression never fully escape the “fog” of low mood and exhaustion—even after completing therapy and medication.

A recent study in the Journal of Positive Psychology links optimism to better responses to SSRI antidepressants, a cornerstone treatment for major depressive disorder. The research suggests that more optimistic individuals are likelier to improve on these medications, and that growing optimism during treatment further increases recovery chances. The findings point to new avenues for mental health care in Thailand and beyond.

In Thai society, where depression remains a hidden burden, these results are particularly relevant. Depression contributes significantly to disability, and cultural factors can hinder help-seeking and adherence to long-term treatment. SSRIs are widely prescribed by mental health professionals across the country, yet responses vary. Understanding the role of optimism could help clinicians tailor care more effectively.

A recent study published in the Journal of Positive Psychology has uncovered a striking link between optimism and the likelihood of responding positively to selective serotonin reuptake inhibitors (SSRIs), a mainstay medication for major depressive disorder. The research suggests that individuals with a more optimistic outlook are not only better positioned to benefit from these antidepressants, but that increases in optimism during treatment also significantly raise the chances of recovery—a finding with important implications for the future of mental health care in Thailand and globally (PsyPost).

A simple daily habit may offer significant support for mental well-being: experiencing awe. New research suggests that small moments of wonder—whether from nature, art, or meaningful experiences—can help ward off depression and stress. For Thai readers, this points to practical, accessible ways to bolster resilience amid rising mental health challenges.

Globally, anxiety, depression, and stress affect millions, including about 1.5 million Thais living with depression, according to Thailand’s Department of Mental Health. Researchers are exploring easy, scalable approaches to support psychological resilience. The latest study indicates that daily encounters with awe—such as watching a sunrise, listening to moving music, or observing the curiosity of a child—may reduce negative emotions and emotional strain over time. These findings align with broader research showing awe’s capacity to improve mood and well-being.

A simple everyday emotion may hold surprising power over mental well-being: new research suggests that experiencing “awe”—that profound sense of wonder sparked by things like nature, art, or meaningful moments—could help fend off depression and stress. According to the latest findings, regular encounters with awe can buffer the emotional toll of daily life, a discovery with practical implications for many, including people across Thailand facing rising challenges to mental health.

A recent study in BMC Geriatrics uncovers how physical activity helps older adults feel less lonely by addressing frailty and depressive symptoms. The findings come at a time when Thailand’s population is aging rapidly, making the topic highly relevant for Thai families and communities. The research shows that regular movement reduces loneliness directly and also through improvements in physical strength and mood, underscoring the value of exercise for dignified, connected aging.

A groundbreaking study published in BMC Geriatrics highlights the intricate web connecting physical exercise, frailty, depression, and loneliness among older adults—a topic of urgent relevance as Thailand’s population rapidly ages. This latest research finds that regular physical activity not only diminishes feelings of isolation but does so by mediating both physical frailty and depressive symptoms, offering hope for millions seeking to age with dignity and connection (BMC Geriatrics).

Loneliness is widely recognized as a severe public health issue among older adults. Defined as a distressing emotional state arising from a perceived lack of meaningful social bonds, chronic loneliness is linked to higher rates of physical and mental health problems, including hypertension, depression, and even elevated mortality (BMC Geriatrics). In the Thai context, where family and communal ties are traditionally considered bedrocks of wellbeing, the cracks showing in these supports due to urbanization, migration, and shifting social structures intensify the risks.

A groundbreaking, nationwide study led by Washington University in St. Louis has found that vagus nerve stimulation—a procedure originally developed to manage severe epilepsy—could offer significant relief for people suffering from treatment-resistant depression (TRD), a condition that does not improve with conventional antidepressant medications. This large-scale research, one of the most comprehensive ever conducted on the subject, could influence insurance coverage policies and potentially change how doctors in Thailand and worldwide approach some of the hardest-to-treat cases of depression (St. Louis Post-Dispatch).

A nationwide study led by a major U.S. university suggests that vagus nerve stimulation (VNS) may provide meaningful relief for those with treatment-resistant depression (TRD). VNS is a surgical option originally developed for epilepsy, now explored as a potential therapy for patients who do not respond to conventional antidepressants. The findings, one of the most comprehensive to date, could influence insurance coverage decisions and reshape approaches to the toughest depression cases worldwide, including in Thailand.

Regular physical activity is proving to be a powerful, accessible tool for mental health across Thailand and the world. New research from Thai universities, alongside global studies, shows movement can reduce stress, anxiety, and symptoms of depression. The latest findings highlight that integrating simple exercise into daily routines is crucial for safeguarding psychological well-being, especially in demanding environments like universities and healthcare education.

Rising anxiety, burnout, and depressive symptoms have prompted public health experts to champion exercise as both preventive and therapeutic. In contemporary Thailand, stressors such as pandemic-related restrictions, economic pressures, and heavy academic workloads are affecting people of all ages. Evidence now positions physical activity as a fundamental pillar of resilience, relevant to students, professionals, and older adults in both urban and rural communities.

A surge of international and Thai research confirms that regular physical activity delivers powerful mental health benefits, reducing stress, anxiety, and symptoms of depression. Recent studies, highlighted in the article “The Mental Health Benefits of Exercise: How Movement Reduces Stress,” and new research from Thai academic institutions, show that integrating movement into daily routines is an essential—and accessible—strategy for safeguarding psychological well-being, especially in high-pressure environments such as universities and healthcare education.

A new study from Imperial College London suggests psilocybin could keep emotional responses to music more intact in depressed patients, while the common antidepressant escitalopram tends to blunt those emotions. Both treatments produced similar improvements in core depressive symptoms, but psilocybin appeared to sustain a richer emotional engagement with music. The research, published in Molecular Psychiatry, and summarized by Medical Xpress, highlights how psychedelic-assisted therapy might influence emotional processing alongside symptom relief. The findings offer potential relevance for Thai audiences where music holds deep cultural and spiritual significance.

A groundbreaking new study from researchers at Imperial College London suggests that the psychedelic compound psilocybin may enhance or preserve depressed patients’ emotional reactions to music, while the commonly prescribed antidepressant escitalopram—an SSRI—can dull these emotions, even though both drugs produce similar clinical improvements in depressive symptoms. The findings, published in Molecular Psychiatry and highlighted by Medical Xpress, provide fresh evidence that psilocybin’s effects on emotional processing could have significant implications for the future of mental health treatment, especially in cultures—such as Thailand’s—where music is integral to social and spiritual life (medicalxpress.com).

A landmark international study has revealed that living with combinations of chronic physical illnesses—such as heart disease, diabetes, lung conditions, or liver problems—more than doubles the risk of developing depression, underscoring the urgent need for Thailand’s healthcare system to integrate physical and mental health care. The research, published in Nature Communications Medicine and based on health data from over 142,000 adults, highlights a concerning link between certain multimorbidity profiles and future depression diagnoses, particularly when illnesses like heart disease and diabetes occur together (Neuroscience News).