#Diphenhydramine

A widely used allergy medication, diphenhydramine—best known by the brand name Benadryl—is facing new scrutiny from health experts, who now argue that its risks outweigh its usefulness, particularly when safer alternatives are available. In a recent review published by leading allergy specialists from Johns Hopkins University and the University of California, San Diego, calls have intensified for this first-generation antihistamine to be pulled from over-the-counter (OTC) and prescription markets in the United States, igniting worldwide interest and concern, including in Thailand where similar medications are popular.

Millions of people across the globe rely on Benadryl, a common over-the-counter allergy medication, for relief from runny noses and itchy skin. However, a fresh wave of scientific evidence is raising serious concern about the long-term safety of its key ingredient, diphenhydramine. A recent study and mounting medical warnings have drawn direct links between regular Benadryl use and a higher risk of developing crippling diseases such as dementia and Alzheimer’s, prompting doctors to urge consumers, including those in Thailand, to reconsider their treatment choices.