Forgetful by design: Dopamine drives memory loss, new worm study hints at human aging and Parkinson’s implications
In a finding that could transform how we understand memory, researchers from Flinders University have shown that forgetting is not simply a failure of the brain but a finely tuned process controlled by a familiar chemical: dopamine. The study, conducted in the tiny nematode Caenorhabditis elegans, suggests that forgetting is an active, purposeful function that helps the brain stay efficient in a world full of competing stimuli. While the work is done in worms, the team emphasizes that the same chemical pathways are conserved across species, including humans, and may illuminate why memory changes with age or in neurodegenerative diseases like Parkinson’s.