#DrugSafety

A widely used allergy medication, diphenhydramine—best known by the brand name Benadryl—is facing new scrutiny from health experts, who now argue that its risks outweigh its usefulness, particularly when safer alternatives are available. In a recent review published by leading allergy specialists from Johns Hopkins University and the University of California, San Diego, calls have intensified for this first-generation antihistamine to be pulled from over-the-counter (OTC) and prescription markets in the United States, igniting worldwide interest and concern, including in Thailand where similar medications are popular.

A wave of new research is drawing unprecedented connections between marijuana use and serious cardiovascular risks, overturning widely-held beliefs that cannabis is relatively harmless. Large-scale studies published in mid-2025 point to a significantly increased risk of heart attack, stroke, and cardiovascular death among users of marijuana—a finding that experts caution should inform personal and public health choices in Thailand and worldwide (The New York Times; Fox News; Virgin Islands Consortium).

As marijuana use undergoes rapid normalization, with legal medical and recreational access expanding across the world, researchers warn that its cardiac dangers are becoming clearer and more urgent. In Thailand, where medicinal cannabis was legalized in 2022 and recreational use remains in legal limbo, these findings arrive as lawmakers and public health officials debate the way forward in marijuana regulation and education (CNN).

New research released in 2025 strengthens concerns about marijuana’s impact on heart health. Large-scale studies show cannabis users face higher risks of heart attack, stroke, and cardiovascular death compared with non-users. These findings arrive as Thailand debates cannabis regulation and public health messaging amid growing access to medical cannabis and ongoing questions about recreational use.

Recent analyses indicate that marijuana’s active compounds, especially THC, can affect blood vessels, heart rate, and blood pressure. In Thailand, where medicinal cannabis was legalized in 2022 and recreational use remains unresolved, experts say the new evidence underscores the need for careful policy making and consumer education. Public health officials note that the tone of messaging around cannabis—often framed as “natural medicine”—must now include clear information about cardiovascular risks.

A prominent New York cardiologist has sounded the alarm on a silent risk lurking in the medication cabinets of millions: phthalates—chemicals used to make soft gel capsules—may significantly increase the risk of heart attacks, according to new research and expert warning. This revelation, which directly affects commonly used medications such as pain relievers, multivitamins, stool softeners, and cold remedies, is poised to raise concern among medicine users globally and in Thailand, where health awareness continues to rise and over-the-counter pharmaceuticals remain readily accessible.

A leading New York cardiologist warns that phthalates—chemicals used to soften gel capsules—may raise the risk of heart attacks. This finding affects everyday medicines such as pain relievers, multivitamins, stool softeners, and cold remedies. The message is timely for Thai readers as over-the-counter medicines are widely available and health awareness grows across the country.

Phthalates, also known as plasticizers, are added to many products to provide flexibility. They are present in a range of items from children’s toys to food packaging, and crucially, in the shells of many oral medications. A senior cardiologist at Mount Sinai notes that phthalates in medical capsules can trigger arterial inflammation and oxidative stress, accelerating artery hardening and narrowing—processes linked to heart disease. A cautious interpretation comes from recent reporting and ongoing research, underscoring the need for careful handling of medicines.