#Endocrinology

A Missouri schoolteacher who was diagnosed with osteoporosis, spondyloarthritis and hypogonadism at age 20 has completed an astonishing 6,050 knuckle pushups in a single 12-hour attempt, an achievement that spotlights how complex causes, careful rehabilitation and persistent strength training can reshape outcomes for people with early-onset bone disease. The feat — livestreamed with local church support, performed in August and now submitted for Guinness World Records review — reads like a human-interest triumph, but it also raises serious, practical questions for clinicians and communities in Thailand about how to detect, treat and safely support younger people living with fragile bones.

A new wave of consumer health guidance is urging people not to abandon their vitamin D supplements in summer, arguing that sunshine alone often falls short—an insight that may surprise residents of tropical countries like Thailand. A recent explainer from Verywell Health reports that experts recommend continuing vitamin D supplements through the warmer months to keep levels steady year-round because sun-derived vitamin D varies widely by skin tone, time outdoors, pollution, and sunscreen use, among other factors. It also reiterates current daily intake guidance—typically 600–800 IU for adults, unless a clinician advises more—and notes that vitamin D3 tends to sustain levels better than D2 in most studies (Verywell Health). For Thailand, where UV radiation is extreme but urban lifestyles limit midday sun and foods are rarely fortified with vitamin D, the message is especially relevant.

A new wave of fitness culture and social media influence has driven increasing numbers of men—including many in their 20s and 30s—to use testosterone supplements in pursuit of enhanced masculinity, muscle gain, and sexual vitality. However, recent research and expert warnings are raising red flags: these supplements, widely marketed as a path to becoming an ‘alpha male,’ can actually cause infertility, with potentially irreversible effects.

Across gyms and online platforms in Thailand and worldwide, testosterone boosters—ranging from herbal products to powerful hormone injections—are being promoted as quick solutions for increased strength, confidence, and libido. This market boom has been further fuelled by aggressive advertising, gym trainer recommendations, and the influence of fitness influencers online. Yet, experts are cautioning that the promised benefits may come at the cost of a man’s future ability to father children, and that misuse can have wider health implications (NDTV).

A groundbreaking long-term study has turned conventional wisdom on its head, revealing that modest rises in blood sugar—not age or testosterone—are a primary driver of sexual decline in men. Presented at ENDO 2025, the Endocrine Society’s annual meeting, these findings highlight that even non-diabetic glucose levels can slow sperm, impair erections, and reduce libido, with important implications for men’s health across Thailand and the world (SciTechDaily).

For years, discussions about aging men’s declining sexual and reproductive health have focused on hormone levels and the inevitable march of time. But this newly published research, led by a respected German endocrinologist, argues that subtle metabolic changes—particularly slight increases in blood sugar—play a more pivotal role than previously recognized. “Although age and testosterone levels have long been considered an impetus for men’s declining sexual health, our research indicates that these changes more closely correlate with modest increases in blood sugar and other metabolic changes,” said a University Hospital in Muenster professor involved in the study. This suggests that lifestyle management and blood sugar monitoring may hold the key to preserving sexual health as men age.

A new international study has revealed that even modest increases in blood sugar levels—not just advanced diabetes—can have a significant negative impact on men’s sexual health as they age, shifting the traditional understanding of male reproductive well-being. The latest findings, presented at the Endocrine Society’s ENDO 2025 annual meeting in San Francisco, spotlight metabolic health, especially mild hyperglycemia, as a key driver in changes to sexual functioning among men, offering a new roadmap for prevention and intervention.

A growing body of new research is shedding light on a potential link between vitamin D supplementation and a reduced risk of developing type 2 diabetes among individuals with high-risk prediabetes. Recent studies suggest that boosting vitamin D levels in those who are already at risk could slow or even prevent the onset of overt diabetes—a finding that may have significant implications for the millions of people in Thailand and worldwide who are living with prediabetes.

Recent global headlines have sparked intense debate and curiosity as leading experts speculate whether the rise in average penis size observed in recent years might be connected to the explosion of weight-loss medications such as Ozempic and Wegovy. A convergence of anecdotal reports and emerging data has prompted scientific and medical communities—and the general public—to seek explanations for this unexpected trend, which could have far-reaching implications for men’s health and societal perceptions in Thailand and worldwide.

A new study published this week has dramatically shifted the landscape of diabetes research, revealing that hyperactivity within a specific set of neurons in the brain—AgRP neurons in the hypothalamus—may drive type 2 diabetes, regardless of weight or obesity. Scientists from the University of Washington demonstrated that by silencing these neurons in mice, blood sugar levels normalized for months, even as the animals’ weight and food intake remained unchanged—a finding that upends decades of established beliefs about diabetes origins and opens compelling new treatment avenues (Neuroscience News).

A growing body of research and expert opinion is highlighting a silent yet serious consequence of excessive abdominal fat in men: a dramatic impact on hormonal balance, sexual health, and fertility. As obesity rates continue to rise—across the world and notably in Asian countries including Thailand—doctors are warning that belly fat is much more than a cosmetic concern. Landmark findings discussed by leading endocrinologists reveal that fat surrounding the waistline acts as an endocrine organ, disrupting testosterone levels and overall male vitality (The News).

Popular health trends recently have seen a surge in interest in so-called “cortisol bellies” and “cortisol faces,” fueled by viral social media posts and a spike in online searches for cortisol-related health advice. These buzzwords, while catchy, attempt to simplify the highly complex biological processes behind how our bodies respond to chronic stress—sometimes sparking unnecessary worry among Thai and global audiences.

Cortisol, often dubbed the “stress hormone,” is produced by the adrenal glands and plays a critical role in helping the body respond to stress. When stress levels rise, so does the production of cortisol, which can affect multiple body systems—regulating metabolism, controlling blood sugar, influencing immune responses, and aiding in fat storage. According to a recent report by the National Post, online searches for information on cortisol, its “trigger foods,” and supposed “cortisol detoxes” have climbed dramatically in the past year, reflecting the growing anxiety about how stress hormones may visibly influence appearance and health (MSN).

Scrolling through TikTok or social media, many Thai readers may have encountered alarming claims asserting that stress-induced cortisol is the main culprit behind stubborn belly fat and unwanted facial changes, often labelled “cortisol belly” and “cortisol face”. However, a recent analysis published by The Conversation dispels much of this online panic, highlighting that the scientific evidence paints a far more nuanced picture and suggesting Thais need not obsess over this hormonal hype.

Social media’s obsession with “cortisol belly” and “cortisol face” has racked up millions of views among Thai users, amplifying fears that the stress hormone cortisol is sabotaging health and appearance. However, scientists and medical experts are pushing back, clarifying that everyday cortisol fluctuations from modern stressors are far from the catastrophic threat depicted in TikTok and Instagram trends—findings that come as a relief for many in Thailand and across the globe. This latest conversation is rooted in a detailed analysis published by a medical researcher through The Conversation, and corroborated by endocrinologists and global health organizations, signaling an urgent need for critical media literacy around health information online.