#Epidemiology

A large Swedish analysis is challenging the long-held belief that higher fitness in youth directly lowers the risk of premature death from diseases such as heart disease and cancer. The findings, published in a leading preventive cardiology journal, suggest that earlier studies may have overstated the life-extending power of adolescence fitness due to unmeasured differences between individuals.

In Thailand, public health campaigns have long linked early-life exercise to longer, healthier lives. School sports programs, Bangkok park running, and rural community fitness initiatives have all drawn on this idea to promote activity. The new research invites policymakers and the public to view fitness as one important piece of a broader health puzzle.

A sweeping new study from Sweden is challenging the widespread belief that higher physical fitness in young people directly leads to a substantially lower risk of premature death from diseases like cancer and heart disease—a notion that has shaped public health messaging globally, including in Thailand. The research, published in the European Journal of Preventive Cardiology (news-medical.net), reveals that previous studies may have overstated the true impact of physical fitness on mortality due to overlooked differences among individuals.

The well-held belief that physical fitness in youth directly causes a lowered risk of early death is being challenged by new research from Uppsala University, which suggests that the true relationship between fitness and mortality may be far more complex than previously thought. The findings, published in the European Journal of Preventive Cardiology, reveal that even random factors—such as accidents—show similar associations to fitness and premature death as diseases, raising questions about the validity of past conclusions on the protective effects of fitness alone.

New Swedish research challenges the idea that youth fitness alone protects against early death. Published in the European Journal of Preventive Cardiology, the study shows the relationship between fitness and mortality may be more complex than previously thought. Even random factors, like accidents, showed similar associations to fitness as diseases did, prompting questions about how much past studies truly prove about fitness’s protective effects.

Thai audiences are familiar with the messaging that regular exercise and strong cardiorespiratory fitness reduce death risk from heart disease or cancer. This view is echoed in public health messaging and Thailand’s Ministry of Public Health guidelines. The Swedish study highlights that many observational findings may overstate fitness effects because not all influencing factors are accounted for.

Three more U.S. states—Louisiana, Virginia, and Missouri—reported their first measles cases of 2025, signaling a broader resurgence. Public health officials say the outbreak now involves at least 27 states, with about 800 confirmed cases. Most cases occur in people who are unvaccinated or whose vaccination status is unknown. Hospitals have seen rising admissions and a small number of fatalities. The surge highlights how quickly measles can spread when vaccination coverage dips and how international travel can seed local outbreaks. In Thailand, a similar pattern has prompted renewed focus on vaccination and outbreak readiness, as reported by national health authorities and international partners.

Three more US states—Louisiana, Virginia, and Missouri—confirmed their first measles cases of 2025 over the weekend, pushing the current outbreak to over half of all US states and marking one of the most significant resurgences in recent years. According to a report by UPI, the total number of confirmed cases across at least 27 states has climbed to 800, with the vast majority being either unvaccinated or of unknown vaccination status. This growing crisis reflects deeper global trends in vaccine coverage and highlights crucial public health lessons for Thailand, where measles cases have also risen sharply over the last two years (UPI, CDC).

A recent discovery in Greenville, North Carolina has put public health surveillance techniques in the spotlight: wastewater samples from a local sewage plant have tested positive for Mpox, the virus formerly known as monkeypox, specifically identifying the clade I strain. The samples, collected between late March and early April, point to the potential presence of the virus in the community, even though no clinical Mpox cases have been officially reported so far. Local health officials are now urging healthcare providers to be vigilant for possible symptoms and to quickly report any suspected infections (WRAL; ABC11).

Wastewater testing in Greenville, North Carolina has detected Mpox, specifically the clade I strain, in samples collected from late March to early April. While no clinical Mpox cases have been officially reported in the area, health officials stress vigilance among clinicians and rapid reporting of suspected infections. This development underscores wastewater-based surveillance as a powerful tool for early outbreak detection.

Thailand and other countries watching infectious diseases should take note. Wastewater-based surveillance (WBS) gained prominence during the COVID-19 era and continues to reveal hidden viral activity by capturing signals from individuals who are pre-symptomatic or have mild infections. According to experts in North Carolina, the presence of clade I mpox virus in wastewater suggests the virus may be circulating locally, even without confirmed cases.