#Fear

A new study shows the brain can learn fear not only from direct experiences but also by making inferences. This challenges how we understand emotional learning and could influence future treatments for anxiety and trauma disorders. Published in Nature on May 14, the research from the RIKEN Center for Brain Science in Japan demonstrates how higher-order emotional learning occurs in the brain, offering insights for neuroscience and mental health care worldwide.

A groundbreaking new study has revealed that the brain is capable of learning fear not just through direct experiences, but also by making inferences—a discovery that could shift our understanding of how humans develop complex emotional responses and may help unravel the roots of anxiety and trauma disorders. The research, published in the prestigious journal Nature on May 14 by a team at the RIKEN Center for Brain Science in Japan, demonstrates for the first time how higher-order emotional learning occurs in the brain, with profound implications for both neuroscience and mental health treatment worldwide (Neuroscience News).

Researchers at a leading U.S. university have uncovered how dopamine, the brain’s reward signal, helps unlearn fear. The discovery, published in the Proceedings of the National Academy of Sciences, could transform treatments for anxiety and PTSD. For Thai readers, this points to new avenues for culturally sensitive therapies that emphasize safety and positive learning.

Across decades, scientists have known the amygdala drives both fear and its extinction. For Thais affected by traumatic events—natural disasters, traffic accidents, or the lingering impact of Covid-19—persistent anxiety and nightmares are common. The new insight into how the brain learns to feel safe offers hope for more effective, locally relevant therapies that reduce stigma around mental health.

Researchers at the Massachusetts Institute of Technology (MIT) have uncovered a crucial mechanism in the brain, revealing how dopamine—commonly known as the “feel-good” neurotransmitter—not only signals danger, but actively helps the brain unlearn fear. The findings, reported this week in the Proceedings of the National Academy of Sciences, could revolutionize potential treatments for anxiety disorders and post-traumatic stress disorder (PTSD), providing hope for millions worldwide—including those struggling in Thailand with trauma-related conditions (SciTechDaily).