#Foodallergy

In a significant breakthrough that could transform the lives of millions of people with dangerous peanut allergies, new research from the UK has found that adults can become desensitised to peanuts through carefully supervised daily exposure. The study, published in the journal Allergy, is the first of its kind to demonstrate that the window for effective allergy treatment may not be limited to childhood, providing a new pathway for severely allergic adults who, until now, have had few options besides lifelong avoidance (The Guardian, King’s College London news release).

A new UK-led study suggests adults with severe peanut allergies can become desensitised through carefully supervised daily exposure. Published in Allergy, the research is the first to show that effective allergy treatment may be possible beyond childhood, offering an option for adults who previously faced limited choices beyond strict avoidance.

Peanut allergy creates constant worry—one mistaken bite can trigger life-threatening reactions. In Thailand, where peanuts appear in many popular dishes, the risk affects social events and travel plans. Oral immunotherapy, or OIT, has mainly been tested in children, leaving adults with uncertain prospects. The Grown Up Peanut Immunotherapy (GUPI) trial, conducted by researchers at a leading London hospital partnership, challenges that assumption. It demonstrates that desensitisation is achievable in adults under rigorous medical supervision.

A major scientific breakthrough suggests food allergies could be reversed, thanks to a key group of immune cells in the gut. Published in Nature on April 16, 2025, the findings could transform how we prevent, treat, and potentially cure food allergies that affect Thai families and strain the health system. Research by a team led by Dr. Dan Littman at NYU Langone Health identifies tolerogenic dendritic cells in the intestines as critical for teaching the immune system to tolerate food proteins rather than attack them.

A major scientific breakthrough has revealed the potential for food allergies—an increasingly common and sometimes life-threatening health issue in Thailand and around the world—to be reversed, thanks to the discovery of a key group of immune cells in the gut. The findings, published on April 16, 2025 in the prestigious journal Nature, have the potential to transform how we prevent, treat, and perhaps even cure food allergies, which have long plagued Thai families and stressed our healthcare system [source].