#GeneticRisk

A surge in recent research has clarified the true drivers behind prostate cancer risk, providing both reassurance and actionable information for millions of men in Thailand and around the globe. Spurred by high-profile diagnoses and persistent myths, these new scientific findings help separate established facts from common misconceptions about this frequently diagnosed but often misunderstood cancer.

Prostate cancer is one of the most prevalent cancers among men worldwide, including in Thailand, where an ageing population and changing lifestyles have brought greater attention to men’s health issues. Although conversations about prostate cancer often focus on concerns after publicized diagnoses of well-known figures, a clearer understanding of genuine risk factors is vital for early detection and prevention. According to recent umbrella reviews of scientific literature, long-standing risk factors such as advancing age, ethnicity, and family history remain central, but new genetic insights and lifestyle considerations are also emerging as important elements shaping an individual’s risk profile (PubMed Review; PMC Article).

A new wave of research is challenging the long-held belief that regular exercise alone is enough to protect the aging brain. The latest findings from a major Vanderbilt University-led study, published in Alzheimer’s & Dementia, reveal that sitting for long hours each day can cause the brain to shrink—regardless of how much you exercise. This discovery has sparked global concern as it highlights the unseen dangers of modern, sedentary lifestyles, even among those who maintain healthy activity levels, and carries special significance for Thailand, a nation witnessing growing urbanization and longer working hours.

A sweeping new international study has reinforced the dangers of elevated lipoprotein(a) – called Lp(a) – showing that any detectable increase in this cholesterol-like molecule is linked to greater risk of heart disease and stroke. The findings, widely reported as the largest investigation of its kind to date, signal a major shift in how health professionals may assess and manage cardiovascular risk, especially in populations such as Thailand where heart disease remains the country’s leading cause of death.