#Genetics

A wave of new research is overturning long-held beliefs about the power of parenting in shaping who we become as adults, with renowned psychologist Michael W. Eysenck’s latest book, “Rethinking Psychology: Finding Meaning in Misconceptions,” spotlighting the ways genetics, more than parenting styles, influence adult personalities. The findings, detailed in a recent report by the Times of India, are likely to spark important conversations in Thai families and among educators who have long assumed nurturing—rather than nature—was the primary driver of children’s lifelong temperaments and mental health Times of India.

A scientific consensus now makes a clear point: there is no meaningful biological basis for racial categories. Yet the social significance of race remains powerful in health, education, and policy around the world. For Thai audiences navigating conversations about ethnicity, heritage, and health, understanding what genetics actually shows is essential.

The Human Genome Project, completed about a quarter of a century ago, transformed how we view human variation. Genetic differences do not cluster into neat racial groups. Instead, most variation exists within any given population, and groups share more similarities than differences. This underscores that race, as a strict biological category, is a social construct shaped by culture and history, not DNA.

Genetics has delivered a powerful verdict in the ongoing discussion about “race”: there is no meaningful biological basis for racial categories, even as their social significance continues to impact lives worldwide. This scientific clarity comes at a time when political and cultural debates, such as recent US presidential orders attacking museum exhibitions that deny race is a biological reality, reignite age-old controversies. For Thai readers navigating conversations on ethnicity, heritage, and health, understanding what genetics truly reveals about human difference is more important than ever.

A wave of new science is reshaping how we understand touch—the earliest and among the most complex senses we rely on daily. Led by researchers at Harvard Medical School, recent work highlights how a diverse network of skin and organ sensors creates our perception of everything from a gentle kiss to a thorn’s prick. The findings also point to how disruptions in touch processing can influence chronic pain and autism, according to a feature by Quanta Magazine.

In a scientific renaissance reshaping our understanding of human sensation, new research led by David Ginty at Harvard Medical School is illuminating the breathtaking intricacies of touch—the first sense we develop and the most complex in both scope and impact on our lives. Recent findings, highlighted in a striking feature from Quanta Magazine, reveal how a rich tapestry of specialized cellular sensors underpins our ability to perceive everything from a lover’s gentle kiss to the prick of a thorn, and show that faulty touch processing may hold the key to conditions like chronic pain and autism (Quanta Magazine).

A new study led by a researcher at East Tennessee State University aims to tackle vitamin deficiencies that affect millions. With a $450,000 grant from a foundation focused on food and agriculture, the team uses machine learning and rapid robotic screening to boost the vitamin content of staple seeds, starting with soybeans. This work offers a practical path to healthier diets worldwide, including in Thailand.

For Thai audiences, the relevance is clear. Thailand has reduced severe malnutrition over the years, but micronutrient gaps—iron, vitamin A, and folate—persist among vulnerable groups such as rural children, pregnant women, and urban poor. These hidden deficiencies can stunt growth and lower productivity. Data from UNICEF Thailand underscores the priority of improving micronutrient intake in Southeast Asia, where rice-based diets often lack diversity.

A groundbreaking study led by Dr. Tianhu Sun of East Tennessee State University (ETSU) aims to tackle one of the world’s most pervasive but invisible health issues: vitamin deficiencies. Armed with a $450,000 grant from the Foundation for Food and Agriculture Research, Dr. Sun and his team are harnessing advanced genetic tools — including machine learning and high-throughput robotic screening — to enhance the vitamin content of staple crop seeds, starting with soybeans. This innovative approach promises realistic, sustainable solutions for improving the nutrient profile of everyday foods worldwide, a change that could echo meaningfully in Thailand and beyond (SciTechDaily).

In a remarkable scientific breakthrough, researchers from the UK and Israel have finally unveiled a new blood group system after decades of investigation. This discovery, sparked by a puzzling case from 1972, has revealed the existence of the MAL blood group, potentially transforming how certain rare patients are treated — an achievement characterized by National Health Service hematologist Louise Tilley as “a huge achievement, and the culmination of a long team effort.”

A landmark international study has identified a new blood group system, unveiled after more than five decades of investigation. Researchers from the United Kingdom and Israel describe the MAL blood group, a finding sparked by a puzzling case from 1972. National Health Service hematologist Louise Tilley calls the discovery “a huge achievement,” marking the culmination of years of teamwork.

In 1972, a pregnant patient’s blood sample lacked a surface molecule once thought universal on red blood cells. It took over 50 years to recognize this anomaly as a distinct blood group system. The 2024 study decoded the genetic basis of this type, AnWj-negative, identifying mutations in the MAL genes. This work deepens our understanding of human blood diversity and could influence how some patients receive transfusions.

Recent groundbreaking research from UCLA Health reveals that puberty triggers significant changes in brain connectivity, which may help explain why some children with chromosome 22q11.2 deletion syndrome, a rare genetic disorder, are at an increased risk for developing neuropsychiatric conditions like autism and schizophrenia. The findings, published in Science Advances, provide new insights into the biological mechanisms underlying these complex conditions, offering hope for future interventions.

Chromosome 22q11.2 deletion syndrome is caused by missing DNA on chromosome 22 and is known to be associated with a higher risk of autism and schizophrenia. Researchers from both UCLA and the Italian Institute of Technology utilized functional brain imaging on both humans and genetically modified mice to explore how this genetic anomaly affects neurodevelopment. They observed that certain brain regions involved in social skills and autism were hyperconnected before puberty and shifted to being under-connected post-puberty. These changes were linked to synaptic activity, with significant implications for affected individuals.

A new study from UCLA Health shows that puberty can reshape brain connectivity in children with chromosome 22q11.2 deletion syndrome, a rare genetic condition. The changes may help explain why these children have a higher risk of neuropsychiatric conditions such as autism and schizophrenia. The researchers published their findings in Science Advances, offering fresh insight into the biology behind these disorders and potential avenues for future interventions.

Chromosome 22q11.2 deletion syndrome arises from missing DNA on chromosome 22 and is linked to increased risks for autism and schizophrenia. Researchers from UCLA and the Italian Institute of Technology used functional brain imaging in both humans and genetically modified mice to explore how this genetic anomaly affects brain development. They found that networks involved in social processing were overconnected before puberty and became underconnected after puberty, with synaptic activity playing a central role in these changes.

A groundbreaking study published in Nature has developed the largest and most detailed single-cell map of how the brain ages, revealing which cell types and regions are most susceptible to changes over time. Conducted by researchers at the Allen Institute for Brain Science, the study mapped over 1.2 million brain cells from both young and older mice, uncovering key vulnerabilities in the hypothalamus—a region crucial for regulating hunger, hormones, and energy balance source.

A new single-cell brain map in Nature reveals which cell types and regions are most affected by aging, offering guidance for Thailand’s aging population. Researchers at the Allen Institute for Brain Science analyzed over 1.2 million brain cells from young and older mice, spotlighting a vulnerability hotspot in the hypothalamus. The hypothalamus regulates hunger, hormones, and energy balance, suggesting links between aging, metabolism, and cognitive changes.

Data from leading neuroscience centers show aging affects the brain unevenly. Rather than a uniform decline, specific cell types undergo distinct gene-expression changes over time. Using single-cell transcriptomics, investigators compared gene activity across life stages akin to human young adulthood and middle age. The study identified 2,449 genes with age-related changes, concentrated mainly in the hypothalamus, pointing to a potential target for interventions aimed at healthy aging and neurodegenerative disease prevention.

A groundbreaking discovery has emerged from recent research led by the German Primate Center and the Max Planck Institute of Molecular Cell Biology and Genetics, highlighting the influence of two human-specific genes on brain development. This research, published on March 27, 2025, unveils how these genes uniquely contribute to the evolution of the human cerebrum, underscoring its unparalleled complexity in the animal kingdom.

The study illuminates the synergistic role these genes play: one gene induces the multiplication of brain progenitor cells, while the other facilitates their transformation into distinct progenitor cells destined to develop into neurons. This finely tuned mechanism is hypothesized to be a pivotal element in the evolutionary trajectory that has led to the exceptionally sophisticated human brain.

A new international study shows how two human-specific genes contribute to brain development, offering clues about the evolution of the cerebrum’s complexity. Researchers from a leading German primate research center and a top molecular biology institute conducted the work. Published in March 2025, the findings illuminate brain evolution and suggest potential avenues for addressing developmental brain disorders.

The study describes a synergistic mechanism: one gene promotes the proliferation of brain progenitor cells, while the other guides these cells to become neuron-producing progenitors. This coordinated process is proposed as a driving factor in the evolutionary path that produced the sophisticated human brain. Beyond evolution, the research hints at new angles for understanding developmental conditions and neurological diseases, with possible therapeutic implications.