#HerbalResearch

Benjakul, a five-herb mixture at the root of Thai traditional medicine, has stood as a resilient survivor through centuries of cultural and medical transformation in Thailand. Revered as “ยาเบญจกูล” in the Thai pharmacopeia, this formula symbolizes a bridge between ancestral wisdom and the evolving demands of contemporary health care. As interest in functional and preventive health sweeps through a modern Thailand seeking alternatives to chemical medicine, Benjakul now finds itself the subject of growing scientific curiosity. Its journey from the apothecaries of ancient healers to the laboratories of pharmaceutical researchers captures a story of not just survival, but continuous reinvention (phar.ubu.ac.th).

For centuries, the humble แห้วหมู (Cyperus rotundus L.)—also known as หญ้าแห้วหมู or หัวแห้วหมู in various parts of Thailand—has held an esteemed place in traditional Thai herbal medicine cabinets and village gardens. Revered across Asia and beyond for its underground tubers, this unassuming sedge has been a symbol of resilience and healing. Today, a wave of renewed scientific interest is validating aspects of its age-old uses, connecting ancestral knowledge with the rigors of modern clinical research. With daily lives increasingly marked by stress, chronic conditions, and lifestyle diseases, Thai readers are seeking both hope and evidence in remedies that endure from the past.

With its signature refreshing aroma and a presence in Thai cuisine, teas, and traditional healing, saranae (สะระแหน่, Mentha × cordifolia) is more than a culinary flourish—it’s a living link between ancient wisdom and modern herbal science. The story of saranae weaves through Thai kitchens, bustling markets, and the annals of both folk medicine and laboratories worldwide, showing how a humble herb continues to captivate health-conscious Thais with its potent, versatile properties.

Deep within the forests, along waterways, and atop rural fences across Thailand, a twisting green vine known as โคคลาน (kok lan), or Mallotus repandus, quietly weaves itself into the cultural and medical heritage of the nation. Revered by traditional healers and often passed down in recipes from older generations, this little-known botanical—alternately called มะกายเครือ, มะปอบเครือ, กระเปี้ยะ, among numerous other names—occupies a unique intersection of folk wisdom and contemporary science. Once sought to quiet burning aches, sooth itching skin, and fortify the liver, Mallotus repandus now finds itself the focus of global biomedical inquiry, testing the boundaries between enduring Thai tradition and modern clinical scrutiny.

Known by many names across the region—กระแจะ, พญายา, ขะแจะ, ตุมตัง, and others—Hesperethusa crenulata is a tree whose bark, stem, and wood have long been treasured in traditional Southeast Asian medicine. In Thailand, the engraved word “กระแจะ” conjures centuries of healing practices, folk wisdom, and even romance, as this herbal ingredient not only soothes physical ailments but is often mentioned in the poetry and cultural traditions of the central plains, the north, and northeast. Today, กระแจะ’s ancient legacy is finding new life as research teams shine the spotlight on its potent phytochemicals and their promising applications for beauty, health, and disease prevention.