#Hibernation

A groundbreaking new study is raising the possibility that humans harbor genetic “superpowers” linked to hibernation, offering hope for advancing treatments against obesity, diabetes, and neurological damage. Researchers believe that genes regulating hibernation—long thought unique to animals like bears and ground squirrels—are present and functional in the human genome, potentially unlocking revolutionary tools for medicine and health maintenance (livescience.com).

This revelation stems from a pair of studies published in the prestigious journal Science, where geneticists at the University of Utah showed that genes regulating core features of hibernation exist in both hibernating mammals and people. If harnessed, this dormant genetic code could help control metabolism, defend the brain against damage, and spark new advances in treating metabolic disorders. For Thai readers, this research signals potential new strategies in national health campaigns battling non-communicable diseases like type 2 diabetes and obesity, two of Thailand’s most urgent public health issues.

Deep within every Thai citizen’s DNA lies a remarkable genetic legacy from humanity’s distant past—hibernation genes that once allowed our ancestors to survive harsh environmental conditions through dramatic metabolic adjustments. Revolutionary research published in the journal Science reveals these dormant genetic programs may hold the key to combating Thailand’s escalating diabetes and obesity epidemics while offering unprecedented insights into human metabolic resilience.

Scientists at the University of Utah have identified conserved genetic elements that regulate hibernation-like metabolic states across mammalian species, including humans. These “hibernation hub genes” control processes that allow animals to bulk up rapidly, enter profound metabolic dormancy, resist neurological damage during blood flow disruptions, and emerge healthy after months of minimal activity. Most remarkably, these same genetic pathways exist within human genomes, potentially accessible through targeted therapeutic interventions.

Revolutionary scientific discoveries published in the prestigious journal Science reveal that humans possess dormant genetic “superpowers” inherited from hibernating mammals that could fundamentally transform treatment approaches for chronic diseases including type 2 diabetes and Alzheimer’s disease—conditions that disproportionately affect Thailand’s aging population and strain the nation’s healthcare infrastructure. This groundbreaking research from University of Utah scientists identifies specific DNA regulatory regions that enable hibernating animals to recover completely from months of physical decline, with these same genetic elements present and potentially activatable in human genomes, opening unprecedented pathways for therapeutic interventions.

The concept of humans carrying dormant genetic “superpowers” for healing may seem like science fiction, but emerging research suggests it’s closer to reality than once believed. In a pair of groundbreaking studies published July 31, 2025, in the journal Science, researchers at the University of Utah have identified specific DNA regions in hibernating mammals that underlie their remarkable resilience—allowing them to recover from months of physical decline without lasting harm. Even more promising, these same genetic elements may be present and potentially activatable in the human genome, opening new pathways for treatments of chronic diseases such as type 2 diabetes and Alzheimer’s disease (Gizmodo; MedicalXpress).