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Rare Guillain-Barré Variant Turns Everyday Sore Throat Into ICU Ordeal — A Thai Perspective on Diagnosis and Hope

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A routine sore throat became a life-changing crisis for Vanessa Abraham, a California speech pathologist. Her condition deteriorated rapidly, landing her in intensive care for weeks and leaving doctors puzzled for months. The case, highlighted by CBS News, spotlights the challenges of diagnosing rare neurological conditions, including a little-known Guillain-Barré syndrome variant. The story resonates beyond the United States and offers lessons for Thai readers navigating similar medical uncertainties.

Abraham’s initial symptoms appeared flu-like: fatigue, body aches, and a raspy voice. Within days, she could barely move or breathe on her own. She was rushed to hospital, intubated, and placed on a ventilator. She recalls the experience as among the most fear-filled moments of her life as clinicians searched for answers while she could not speak or eat. The medical team’s tireless efforts eventually revealed a diagnosis four months later: the pharyngeal-cervical-brachial (PCB) variant of Guillain-Barré syndrome—a rare form that affects nerves in the throat, neck, and arms.

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