#IL17

A new study from researchers at MIT and Harvard Medical School reveals that the immune molecule IL-17 can influence social behavior and anxiety by acting directly on specific brain regions. The research shows IL-17 has a dual role: it enhances sociability by dampening neuron activity in the cortex, while it increases anxiety by heightening excitability in the amygdala. In effect, IL-17 appears to function as a neuromodulator, linking immune system activity with how we feel and behave. This insight could inform future approaches to conditions such as autism and depression, according to the study’s findings and interpretations from leading neuroscience outlets.

Recent research led by MIT and Harvard Medical School has uncovered the intriguing role that the immune molecule interleukin-17 (IL-17) plays in shaping social behavior and anxiety by acting directly on specific brain regions. This groundbreaking study reveals that IL-17 serves dual functions: enhancing sociability by reducing neuron excitability in the brain’s cortex and triggering anxiety by increasing excitability in the amygdala. These findings suggest IL-17 acts like a neuromodulator, drawing a fascinating link between immune system activity and behavioral outcomes, with potential implications for the treatment of conditions like autism and depression (Neuroscience News).