#JAMA

Revolutionary clinical trial evidence demonstrates that older adults at risk of dementia can significantly improve cognitive function through strategic lifestyle modifications including structured exercise, brain-healthy nutrition, social engagement, and cognitive training, with supervised programs offering measurably superior benefits compared to self-guided approaches. The groundbreaking two-year U.S. POINTER study, presented at the Alzheimer’s Association International Conference and published in JAMA, enrolled over 2,100 adults aged 60-79 and documented cognitive improvements in both intervention groups, with structured coaching and regular group sessions providing modest but meaningful additional advantages over independent lifestyle changes. For Thailand, where the aging population is surging toward super-aged society status and dementia care increasingly relies on community and family support systems, these findings provide crucial evidence that practical lifestyle interventions can be systematically integrated into public health infrastructure to protect brain health across entire populations according to Smithsonian Magazine reporting, Alzheimer’s Association conference releases, and JAMA publication records.

A major clinical trial has found that older adults at risk of dementia can improve their thinking skills through everyday changes in exercise, diet, social engagement and brain training—and that a more structured, supervised program offers a modest but meaningful extra benefit over a self-guided approach. The two‑year U.S. POINTER study, presented at the Alzheimer’s Association International Conference and published in JAMA, enrolled more than 2,100 adults aged 60–79 and reported cognitive gains in both study arms, with a slight edge for those receiving high‑touch coaching and regular group sessions. For Thailand, where the number of older persons is surging and dementia care is increasingly delivered in communities and families, the findings underscore that practical lifestyle supports can be built into public health and social systems to protect brain health at scale (Smithsonian Magazine; Alzheimer’s Association AAIC release; JAMA PubMed record).