#Medical

A new study from the Institute of Science and Technology Austria (ISTA) introduces a brain organoid model that includes microglia, the brain’s immune cells. This addition enhances the model’s ability to simulate inflammation and improves prospects for safer pharmaceutical testing during pregnancy. The development is timely for global health and aligns with Thai prenatal care policy ambitions to refine safe medication guidelines for expectant mothers.

Historically, brain organoid models lacked microglia, limiting their accuracy in mimicking how the human brain responds to infections. By incorporating microglia, researchers can better understand how the developing nervous system reacts to infections such as Rubella, a concern for pregnant women due to potential fetal complications. In Thailand, where maternal and neonatal health remains a policy priority, this research supports national efforts to reduce congenital risks and strengthen prenatal care.

A breakthrough in bioelectronics offers a glimpse of a less invasive future for treating congenital heart defects in infants. Researchers have developed the world’s smallest injectable pacemaker that powers itself from the body’s fluids and dissolves after temporary use, reducing the need for open-heart procedures.

The ultra-miniature device is designed to be injected via syringe and works with a soft, chest-worn monitor. The monitor detects irregular heart rhythms and activates the pacemaker through the skin with a light pulse. This approach aims to simplify care while protecting the health of young patients.