#Methylphenidate

A major international study shows the brain chemical dopamine plays a dual, sophisticated role in learning: it encourages fast, effortful working-memory strategies in some people while also boosting slower, trial-and-error reinforcement learning when dopamine is pharmacologically increased. The experiment combined brain imaging, drugs commonly used in ADHD treatment, and computational models to show that a person’s natural dopamine production predicts whether they lean on mental “scratchpad” strategies, while methylphenidate (Ritalin) amplifies incremental learning and an antipsychotic (sulpiride) reduces working-memory reliance (Nature Communications study) and was summarized in coverage of the findings (PsyPost summary).