Marathon Running Linked to Temporary Brain Changes: Reassessing the Impact on Myelin
In an intriguing new development for athletes and neuroscientists alike, a study led by researchers from the University of the Basque Country and published in Nature Metabolism has revealed that marathon running can temporarily deplete myelin content in the human brain. This transient change, however, appears fully reversible within two months, offering reassurance to endurance athletes concerned about potential long-term neural impacts.
With Bangkok experiencing a growing marathon culture, this insight is timely for Thai enthusiasts who routinely test their endurance over the challenging 42-kilometer stretch. The study sheds light on the brain’s adaptability—or “metabolic myelin plasticity”—by suggesting that under intense physical exertion, the brain might utilize myelin lipids as a secondary energy source. This finding is of particular interest given that glycogen depletion during prolonged exercise may necessitate alternative metabolic adaptations.