#Myokines

A single 45-minute exercise session raised cancer-fighting proteins in survivors’ blood. (Study: A single bout of resistance or high-intensity interval training increases anti-cancer myokines and suppresses cancer cell growth in vitro in survivors of breast cancer) (https://pmc.ncbi.nlm.nih.gov/articles/PMC12259798/).

The study tested blood before exercise, immediately after, and 30 minutes later. (https://pmc.ncbi.nlm.nih.gov/articles/PMC12259798/).

Researchers found short-term rises in decorin, interleukin-6, and SPARC after exercise. (https://pmc.ncbi.nlm.nih.gov/articles/PMC12259798/).

The conditioned blood slowed growth of aggressive breast cancer cells in the lab. (https://pmc.ncbi.nlm.nih.gov/articles/PMC12259798/).

Groundbreaking research from Edith Cowan University demonstrates that a single forty-five minute exercise session can trigger release of muscle-derived proteins that significantly inhibit aggressive breast cancer cell growth in laboratory settings. The study, involving thirty-two breast cancer survivors, found that blood serum collected immediately after both resistance training and high-intensity interval training reduced triple-negative breast cancer cell proliferation by up to approximately thirty percent when applied to cultured cancer cells.

A new set of experiments suggests that a single 45‑minute session of exercise can flood the blood with muscle‑derived proteins that slow the growth of aggressive breast‑cancer cells in the laboratory — a finding that adds biological weight to years of epidemiological evidence linking physical activity with lower recurrence and mortality. Researchers at Edith Cowan University in Perth collected blood from 32 breast‑cancer survivors before, immediately after and 30 minutes following either a resistance training session or a high‑intensity interval training (HIIT) session; serum taken after exercise raised levels of several myokines (muscle‑secreted signalling proteins) and, when applied to cultured triple‑negative breast‑cancer cells, reduced tumour cell growth by up to about 30 percent in vitro [ScienceAlert; SpringerLink; Edith Cowan University newsroom].

A groundbreaking new study from researchers at Edith Cowan University (ECU), published July 2025 in the journal Breast Cancer Research and Treatment, has revealed that just one session of exercise—either resistance training or high-intensity interval training (HIIT)—can cut cancer cell growth by as much as 30% in breast cancer survivors. The results reinforce the idea of exercise as an accessible and powerful tool for combating cancer, even beyond its already well-established role in post-treatment recovery and long-term well-being.

Extraordinary scientific breakthrough research from Australia’s prestigious Edith Cowan University, published in the internationally renowned journal Breast Cancer Research and Treatment, has revealed that just one individual exercise session—whether resistance training or high-intensity interval training—can dramatically reduce cancer cell growth by up to 30% among breast cancer survivors. This groundbreaking discovery fundamentally challenges traditional assumptions about exercise’s cancer-fighting mechanisms, demonstrating that measurable anti-cancer biochemical changes occur immediately after single workout sessions rather than requiring months of consistent training to achieve meaningful results.