#Nad

In the world of health and beauty, a new wave of supplements promises to turn back the clock by reviving cellular powerhouses. The so‑called NAD+ boosters, including nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR), have been marketed as shortcuts to youth, radiant skin, sharper energy, and even longer life. But the newest research suggests a more cautious verdict: these pills can raise blood levels of a vital coenzyme, but the leap from higher NAD+ to visible anti‑aging or cosmetic benefits is not yet proven, and the long‑term safety and cost are real considerations for Thai families plotting their health budgets.

A new study from researchers at the University of California, Irvine, examines how a combination of vitamin B3 and green tea extract can momentarily restore youthful energy balance in aging mouse brain cells in a controlled lab setting. Published in GeroScience, the research suggests that certain cellular aging processes may be reversible, hinting at future strategies to address dementia risk in Thailand’s rapidly graying society. Yet scientists caution that the findings are confined to dish-based experiments and have not been tested in living animals or humans. Significant challenges remain in determining safe dosages, delivery methods, and overall applicability.

Groundbreaking laboratory research from the University of California Irvine demonstrates that combining vitamin B3 with green tea extract can restore youthful energy balance in aging mouse brain cells within 16-24 hours, potentially clearing Alzheimer’s-associated protein deposits and revitalizing cellular cleanup systems. The study, published in GeroScience, reveals that specific aspects of neuronal aging may be surprisingly reversible at the cellular level, offering hope for Thailand’s rapidly expanding elderly population facing escalating dementia risks. However, leading researchers emphasize critical limitations: these remarkable effects occurred only in laboratory dish conditions, have not been tested in living animals or humans, and face significant challenges in dosage, delivery, and safety that must be resolved before any therapeutic applications emerge.

A lab study from the University of California, Irvine reports that a simple combination of nicotinamide (a form of vitamin B3) and EGCG, the antioxidant in green tea, restored “youthful” energy balance in aging mouse neurons and helped clear Alzheimer’s‑linked protein clumps within 16–24 hours. The work, published in the journal GeroScience, suggests that some aspects of brain cell aging may be surprisingly reversible — at least in a dish — but experts caution that the findings have not yet been tested in living animals or people, and that dosing, delivery and safety remain open questions (GeroScience, Springer; PubMed; UC Irvine news; StudyFinds summary).

NAD supplements have risen as a notable wellness topic, promising boosts in energy, metabolism, and longevity. Nicotinamide adenine dinucleotide (NAD) is a molecule key to cellular energy production and renewal. As researchers explore its potential, the conversation balances optimism with careful scrutiny.

NAD operates as NAD+ and NADH, transforming food into usable energy. A seasoned nurse practitioner notes its vital role in cellular health, supporting energy production, DNA repair, and immune function. Since NAD+ levels tend to decline with age, interest in supplementation grows, particularly among adults over 30 who seek to maintain vitality.