#NAD

Groundbreaking laboratory research from the University of California Irvine demonstrates that combining vitamin B3 with green tea extract can restore youthful energy balance in aging mouse brain cells within 16-24 hours, potentially clearing Alzheimer’s-associated protein deposits and revitalizing cellular cleanup systems. The study, published in GeroScience, reveals that specific aspects of neuronal aging may be surprisingly reversible at the cellular level, offering hope for Thailand’s rapidly expanding elderly population facing escalating dementia risks. However, leading researchers emphasize critical limitations: these remarkable effects occurred only in laboratory dish conditions, have not been tested in living animals or humans, and face significant challenges in dosage, delivery, and safety that must be resolved before any therapeutic applications emerge.

A lab study from the University of California, Irvine reports that a simple combination of nicotinamide (a form of vitamin B3) and EGCG, the antioxidant in green tea, restored “youthful” energy balance in aging mouse neurons and helped clear Alzheimer’s‑linked protein clumps within 16–24 hours. The work, published in the journal GeroScience, suggests that some aspects of brain cell aging may be surprisingly reversible — at least in a dish — but experts caution that the findings have not yet been tested in living animals or people, and that dosing, delivery and safety remain open questions (GeroScience, Springer; PubMed; UC Irvine news; StudyFinds summary).