#Neurogenesis

A new study from Karolinska Institute in Stockholm provides fresh evidence that the adult brain can generate new neurons, even in old age. Published in Science, the findings challenge the belief that brain growth ends in childhood and open doors to potential treatments for neurological and mental health conditions. For Thai readers, the research highlights implications for dementia, stroke recovery, and lifelong learning in an aging society.

Researchers examined brain tissue from 46 individuals aged from infancy to 78 years, using advanced single-cell genomics. They focused on the hippocampus, a region essential for memory and learning, and found neural progenitor cells actively dividing in adulthood alongside mature neurons. The results align with animal studies that have long shown adult stem cells in the brain.

A groundbreaking study from Sweden has provided compelling evidence that the adult human brain continues to generate new neurons well into old age, debunking the long-standing belief that brain cell growth halts after childhood. This discovery, published in the journal Science and highlighted in a recent Gizmodo report, offers new hope for future treatments of neurological and psychological disorders, and reshapes our understanding of the brain’s lifelong potential.

For decades, it was widely believed—taught both in schools and medical textbooks—that the human brain reached its full complement of neurons in early life, and that no new neurons were formed past childhood. While previous studies hinted at ongoing brain cell growth, scientific opinion remained split, with some researchers finding scant evidence for adult neurogenesis and others reporting clear signs. The confusion was particularly acute when it came to humans, since much of the existing evidence came from studies in animals such as mice or pigs.