#Neuropathy

A surge in health-conscious supplement use has brought a renewed warning about vitamin B6 toxicity, as fresh research and regulatory concern reveal that excessive intake may be harming more people than previously recognized. Australia’s medicines regulator, the Therapeutic Goods Administration (TGA), recently admitted it may have underestimated the scope of vitamin B6 side effects—especially nerve damage linked to prolonged high-dose use—prompting the body to reconsider how this over-the-counter supplement is sold (The Conversation).

A century-old anatomical puzzle may finally provide relief for millions battling diabetic nerve pain, according to groundbreaking new research that has reignited scientific interest in the Nageotte nodule—a little-known cellular structure first described over a hundred years ago. The latest study, led by scientists at the University of Texas at Dallas (UT Dallas), reveals that these tiny cell clusters are not only abundant in people with diabetes, but likely play a crucial role in the development of debilitating peripheral neuropathy, a leading cause of chronic pain, diminished mobility, and even amputation worldwide.