#Neuroplasticity

A groundbreaking new review drawing on the legendary Harvard Study of Adult Development has revealed that maintaining mental sharpness into your 80s is less about genetics and more about daily habits—many of which can be changed starting today. The research, which echoes across decades of global brain science, warns that seven specific habits are particularly damaging to long-term cognitive health, while offering evidence-based alternatives that can help Thai readers cultivate resilience and alertness well into old age VegOutMag.

A ground-breaking study involving nearly 20,000 individuals has revealed that persistent negative thoughts aren’t just distressing—they may also be physically altering the very structure and functioning of your brain. In research led by a team at Amen Clinics, a prominent US-based brain health diagnostics institution, scientists used brain scans and cognitive data from individuals diagnosed with anxiety disorders, discovering clear links between what is called the “negativity bias” and abnormal patterns in several critical brain regions. For Thai readers, this may shed new light on mental health struggles and introduces opportunities for science-backed practices to improve national wellbeing.

A groundbreaking approach to overcoming negative thoughts has emerged from the field of neuropsychiatry, offering hope for millions who struggle with persistent self-doubt and emotional overwhelm. A leading US brain health expert has championed a practical, evidence-based method that uses simple writing exercises to retrain the mind and foster a more positive outlook, harnessing the brain’s remarkable ability to rewire itself—known as neuroplasticity. This mental training strategy holds particular promise for Thai readers, many of whom seek effective ways to manage stress and emotional health amid the pressures of modern life.

Curiosity, often dismissed as a mere childhood impulse, is gaining renewed scientific recognition as a core engine of learning and adaptability, according to emerging neuroscience research highlighted in a recent Big Think analysis published on May 12, 2025. The article, “How curiosity rewires your brain for change,” draws on contemporary studies to reveal how curiosity not only drives exploration but may also rewire our brains to buffer against stress and navigate change more effectively—a message with profound implications for Thai students, workers, and lifelong learners facing rapid social and technological transformation.

A groundbreaking new study from the University of Michigan has found that a single dose of a novel psychedelic compound can produce weeks-long improvements in brain flexibility—a finding that could pave the way for innovative therapies targeting depression, PTSD, and neurodegenerative diseases. Using advanced research techniques on laboratory mice, scientists observed that the psychedelic 25CN-NBOH not only changed behavior in the short term but led to sustained cognitive enhancements, suggesting a fundamental shift in our understanding of how these substances might promote long-term brain health (Neuroscience News).

A groundbreaking pilot study has unveiled a fascinating aspect of human endurance, where during prolonged strenuous exercise like marathons, the brain might begin to ’eat’ itself by consuming its fatty sheath—myelin—for fuel. This unexpected finding adds a novel layer to our understanding of neuroplasticity, showcasing a radical adaptation strategy when glucose levels in the brain plummet.

The study, conducted by neuroscientists in Spain, involved 10 marathon runners who underwent MRI scans before and after their races. It was observed that 24 to 48 hours following the grueling 42-kilometer run, there was a significant reduction in myelin levels within regions of the brain crucial for motor skills, coordination, sensory, and emotional processing. Fortunately, these changes were not permanent. Just two weeks after the race, the myelin levels began to recuperate, and a full recovery was noted in most participants within two months.

In a fascinating new piIot study, neuroscientists suggest that the human brain may begin to “eat itself” during strenuous endurance exercises such as marathon running. This revelation comes from a team of researchers in Spain who observed intriguing changes in the brain’s white matter among marathon runners. Their findings present a novel form of neuroplasticity that could be crucial for maintaining cerebral functionality under extreme physical stress.

The researchers, led by Pedro Ramos-Cabrer and Alberto Cabrera-Zubizarreta, conducted MRI scans on the brains of ten marathon runners—eight men and two women—both before and after a 42-kilometer race. The scans depicted a marked decrease in myelin, a fatty layer that insulates nerve fibers and is integral for efficient communication between neurons. This reduction appeared uniquely pronounced in regions associated with motor function, coordination, sensory processing, and emotional integration. Remarkably, myelin levels began to rebound 24 to 48 hours post-race and were largely restored within two months for the six participants who continued with periodic scans.