#Neuroscience

A sweeping new meta-analysis conducted by researchers at the Max Planck Institute for Human Cognitive and Brain Sciences has produced the most detailed map yet of the brain activity involved in reading, revealing distinct patterns of neural engagement for everything from individual letters to full texts. Summarizing findings from 163 previous studies, the review—recently published in Neuroscience & Biobehavioral Reviews—offers a nuanced framework that could influence education strategies and interventions for reading difficulties worldwide, including in Thailand (medicalxpress.com).

In a discovery that stretches the boundaries of memory research, scientists have recently shed light on “jamais vu”—the rare and unsettling feeling that something deeply familiar suddenly appears strange or unrecognizable. While most Thais are familiar with the spine-tingling phenomenon of déjà vu, the eerie sense that one has lived through a moment before, its lesser-known counterpart, jamais vu, proves to be even more uncanny, and researchers say it holds important clues to the workings of the human brain (ScienceAlert).

A new meta-analysis by the Max Planck Institute for Human Cognitive and Brain Sciences offers the most detailed understanding to date of how our brains process written language—a development with profound implications for education, mental health, and addressing literacy challenges in Thailand and worldwide. Published in the journal Neuroscience & Biobehavioral Reviews, the study summarizes decades of neuroscience research, analyzing data from 163 brain imaging studies to construct a highly detailed map of the brain regions activated during different types of reading tasks, from letters and words to sentences and passages.

A groundbreaking study published in Nature has delivered unexpected results in the scientific quest for understanding consciousness, challenging two of the most prominent theories about its origins and offering fresh insights with potential to reshape clinical neuroscience worldwide. The findings reveal that neither Integrated Information Theory (IIT) nor Global Neuronal Workspace Theory (GNWT)—the cornerstones of modern consciousness research—can fully account for how human conscious experience arises, redirecting scientific focus to the brain’s sensory areas and raising critical implications for patient care and brain injury diagnosis (Neuroscience News).

A new study has revealed that lucid dreaming is not simply a vivid form of REM sleep, but constitutes an entirely unique state of consciousness—one with neurological hallmarks that set it apart from both waking and ordinary dreaming. This major breakthrough in sleep science, published in The Journal of Neuroscience, offers tantalising implications for understanding the human mind and may one day help people harness more of their cognitive potential—even outside of sleep.

A recent study has unlocked key insights into the brain mechanisms behind why some individuals are more inclined to help others, highlighting the powerful role of social bonding and neural responses. The findings, based on experiments with rats, provide a scientific window into the roots of prosocial behavior—those acts of kindness and assistance that strengthen communities, families, and friendships. For Thai readers, these results could help explain the diversity of helpfulness observed in daily life, from simple acts of hospitality to the outpouring of aid during national disasters.

A groundbreaking new study has found that preschool children’s brains respond differently when stories are shared through live book reading versus on a screen, suggesting that how children experience stories may impact key aspects of their social and cognitive development. The research, published in the journal Developmental Science, used advanced neuroimaging technology to observe children’s brain activity during both types of storytelling—a live reading from a book and a recorded story paired with images on a screen (PsyPost).

A new era in the scientific quest to pinpoint where consciousness arises in the brain has arrived with the publication of an unprecedented collaborative study, revealing tantalizing clues—but offering no final answers. International neuroscientists, working with the backing of major institutions, have tested the top two competing theories about consciousness using sophisticated brain imaging across hundreds of participants, uncovering emerging insights with far-reaching implications for clinical medicine and philosophical understanding.

A groundbreaking international review has found that even brief, high-intensity physical activity—like brisk walking for just a few minutes at a time—can significantly reduce the risk of dementia and slow cognitive decline as people age. Published in The Lancet and led by researchers from Norway’s Cardiac Exercise Research Group in collaboration with the Queensland Brain Institute, this study underscores the immense brain benefits of “microtraining” and calls for urgent updates to global and Thai physical activity guidelines to reflect these new findings (Neuroscience News).

A groundbreaking scientific study has found that venturing into unfamiliar environments before studying can significantly enhance the brain’s capacity to absorb and retain new information, offering fresh strategies for Thai students and lifelong learners seeking to maximize their educational outcomes. The research, which has implications from primary education to university entrance exams and professional development in Thailand, underlines the value of combining experiences of novelty with the comfort of familiarity to optimize memory and learning.

The formative years from age 5 to 12—often referred to as “middle childhood”—are gaining critical attention in new research, pushing back against long-standing misconceptions that these years are merely a pause between the milestones of early childhood and adolescence. Recent analyses, highlighted by scholars and major health organizations, are reframing this period as a dynamic stage that lays the foundation for lifelong mental, academic, and social well-being [Psychology Today].

Long viewed as a “waiting room” in both scientific literature and public perception, the years between 5 and 12 have not received the same focus as the “first 1,000 days” or the dramatic changes of adolescence. Yet, experts now warn this oversight could be costing societies dearly, especially as recent studies have detailed how brain development, emotional regulation, cognitive skills, and social habits solidify during these so-called “quiet years”. For families and educators in Thailand—where cultural values emphasize respectful quietude and conformity in young students—such findings are especially significant.

A groundbreaking study published in Nature Communications reveals that the key to success in complex environments is not rigid adherence to instinct or imitation, but flexibility in learning—blending social and individual strategies as circumstances require. The research, leveraging the video game Minecraft as a sophisticated simulation platform, provides fresh insights into how humans dynamically adapt their approach to challenges, offering profound implications for education, cognitive science, and social development.

For Thai readers, the findings are especially significant as Thailand modernizes its education system and workplace culture, aiming to cultivate 21st-century skills. Rapid changes driven by digital transformation and social connectivity make adaptability more essential than ever. This new evidence underscores the value of teaching students and workers to toggle between learning from personal experience and absorbing cues from peers—a balance that could power both academic and workplace achievement in Thai society.

A new study by neuroscientists has provided the most detailed picture yet of how children’s brains function differently when reading physical books compared to viewing stories on screens, with important implications for educational strategies in Thailand and worldwide. According to research highlighted in a recent PsyPost report, distinct neural responses are triggered in young children during traditional book reading versus screen-based engagement—a finding raising vital concerns as digital devices become ubiquitous in both homes and classrooms.

A new study published in The Lancet has shed light on the powerful neuroprotective effects of regular exercise, highlighting its vital role in promoting healthy brain ageing and potentially reducing the risk of dementia and other cognitive diseases. The findings are of particular significance for Thai readers, as Thailand faces an ageing society with rising concerns over brain health and dementia rates among older adults.

With Thailand’s population shifting rapidly towards the elderly—projections estimate that over 20% of Thais will be aged 60 or over by 2025—the burden of age-associated cognitive decline has become a pressing issue for families and the healthcare system alike. The newly published research underscores the importance of fitness, adding scientific weight to long-standing folk wisdom encouraging an active lifestyle for “kaeng raeng”—robust health. The study, titled “Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing,” explains that physical activity goes beyond maintaining muscle and heart health: it triggers specific molecular and cellular mechanisms that directly protect brain tissue from age-related degeneration.

In a development that could rewrite neuroscience textbooks, researchers have identified a specific brain region believed to be central to human consciousness, offering new hope for brain injury patients and transforming how medicine, law, and education understand the mind. This groundbreaking discovery, led by an international team of neuroscientists and reported in a recent Earth.com article, marks a critical step in unraveling one of science’s deepest mysteries: where and how consciousness arises in the human brain Earth.com.

A wave of new research is upending long-held beliefs about the “feel-good” brain chemical serotonin, suggesting its roles in everyday decision-making are far more intricate than previously thought. A recent article from MedicalXpress spotlights studies unveiling a complex serotonin system, revealing dynamic activity patterns that could revolutionize how scientists—and potentially clinicians—approach human behavior, mental health, and treatment strategies MedicalXpress.

For decades, serotonin has been popularized as a simple chemical messenger regulating mood, with its influence on happiness, depression, and anxiety immortalized in everything from health textbooks to Thai social media memes. In Thailand, where mental health awareness campaigns are gaining momentum and selective serotonin reuptake inhibitors (SSRIs) remain a first-line treatment for depression, understanding how serotonin truly affects everyday choices has wide-ranging implications. Scientific dogma once held that serotonin’s main function was to broadcast a basic reward or punishment signal, essentially nudging people toward or away from certain actions.

A major international research project led by the University of Ottawa is upending decades-old assumptions about how serotonin neurons function in the brain, with profound potential implications for treating mood disorders such as depression and understanding how our brains make binary decisions. Published in Nature Neuroscience on April 25, 2025, the study reveals that serotonin neurons—long thought to act as isolated units—actually form interconnected networks that collaborate and compete, orchestrating the brain’s serotonin output in ways far more complex than previously believed. The findings mark a major shift in neuroscience’s understanding of one of the brain’s most important neurotransmitter systems and open new avenues for targeted mental health therapies (Neuroscience News).

A growing body of research continues to affirm what fitness enthusiasts have long suspected: regular physical activity is one of the most potent defenses against memory loss and cognitive decline. A new wave of studies in 2025 offers fresh, compelling evidence that working out does more than build muscles—it fortifies brain resilience, providing a potential shield against conditions like dementia and memory impairment. For Thai readers seeking practical, research-backed insights on preserving mental sharpness as they age, the latest findings carry both hope and actionable takeaway.

A recent collaboration between Chinese and French neuroscientists has produced groundbreaking findings on the neural mechanisms underlying consciousness, signaling potential advances in how the human mind is understood and how altered states of awareness might be approached in medical settings. This research, as reported by the South China Morning Post, has captured the global scientific community’s attention by illuminating the intricate neural networks believed to govern conscious experience, and it raises important implications for the future of neuroscience, medicine, and even philosophy.

A growing body of scientific research is shedding new light on the powerful ways that regular exercise can protect the brain as people age, supporting sharper thinking and potentially lowering the risk of dementia. The latest review, published in The Lancet, details multiple neuroprotective mechanisms by which physical activity benefits the ageing brain, amplifying longstanding calls for Thais—and people worldwide—to prioritise fitness for lifelong cognitive health The Lancet.

This news carries significant implications for Thailand’s rapidly ageing society. With more than 15% of the population now over 60, the Kingdom faces surging rates of dementia and related disorders, making brain health a national priority. While genetics and other factors do play a role, the new review points out that lifestyle interventions like exercise remain among the most accessible and cost-effective measures to promote cognitive resilience in later years.

Human understanding of how the brain creates, stores, and retrieves memories may be on the verge of a radical transformation, as cutting-edge research from a team at Trinity College Dublin has upended decades-old theories about memory. Led by a leading neuroscientist at the college’s Institute of Neuroscience, this fresh research shows that memories are not locked away in single neurons as previously thought, but rather stored via complex interactions between groups of special neurons known as “engram cells.” The implications for neurological disorders, learning, and even the way we regulate our bodies are profound.

A surge of new research is reshaping scientific and medical understanding, revealing that sex hormones such as estrogen and progesterone are not confined to reproduction—these hormones are powerful regulators that sculpt brain structure, function, and disease susceptibility. This growing insight is sparking calls for a biomedical revolution, advocating new approaches to treating neurological disorders and personalized medicine strategies that could transform lives in Thailand and globally.

For most of the twentieth century, hormones like estrogen and testosterone were primarily discussed for their roles in fertility, menstruation, pregnancy, and sexual development. However, as detailed in recent exposés from outlets such as the New York Times and a landmark review in Brain Medicine, researchers have steadily revealed that estrogen, in particular, promotes the health of nearly every organ in the human body, with a special, underappreciated influence on the brain itself (New York Times). This is not just a Western scientific curiosity—its implications touch on global health, with Thai neuroscientists and medical practitioners urged to take note.

A groundbreaking new study published by an international research team led by the University of Ottawa is challenging decades-old beliefs about how serotonin works in the brain, uncovering a sophisticated web of interactions among serotonin neurons that could help redefine the treatment of mood disorders such as depression. Researchers found that instead of acting independently, clusters of serotonin neurons in the brainstem actively compete and collaborate, shaping both the timing and manner of serotonin release across different brain regions—a finding that overturns prior conceptions of a uniform serotonin signal and points to a more nuanced understanding of brain function and behavior (Neuroscience News).

As the intensity of exam season ramps up in Thailand’s schools, families across the country find themselves searching for ways to support students under mounting pressure. Recent neuroscientific research, as discussed in a widely circulated article by a prominent neuroscientist in The Times, provides fresh insights into how caregivers can help children handle academic stress, with implications that resonate powerfully for Thai households navigating national exams and university entrance tests source.