#Newtherapies

A new discovery is sending ripples through the medical world: scientists have identified a gene called PHGDH not just as a bystander but as a direct cause of Alzheimer’s disease, potentially changing the diagnosis and treatment of this devastating condition. Uncovering a previously unknown function of this gene, researchers have also pinpointed a candidate drug-like compound that may one day prevent or slow the disease in its earliest stages – a major leap forward, especially for aging societies like Thailand.

A new study reshapes our understanding of Alzheimer’s disease. Researchers identify the PHGDH gene not just as a marker, but as a driver of brain changes linked to Alzheimer’s. They also spotlight a candidate drug-like compound that could slow the disease in its earliest stages. The finding holds particular relevance for aging societies like Thailand, where dementia care poses rising health and social challenges.

Globally, Alzheimer’s is the most common form of dementia, affecting roughly one in nine people aged 65 and older. In Thailand, the rapidly growing elderly population brings heightened concerns about cognitive decline and dementia care. While rare genetic mutations are known to cause some cases, most Alzheimer’s cases arise spontaneously. This research offers fresh scientific insight and potential hope for families and health systems facing dementia.