#Nicotinamide

A large wave of new evidence is adding to the chorus of dermatologists recommending nicotinamide, a form of vitamin B3, as a daily supplement to help prevent new skin cancers in people at high risk. In a growing body of research, this common dietary ingredient—already familiar to many as a multivitamin staple—appears to reduce the number of new skin cancer cases when taken regularly over time. The findings come amid a broader push in public health to combine everyday wellness habits with proven medical prevention strategies, a message that resonates deeply in sun-soaked Thailand where outdoor work and cultural gatherings intensify UV exposure.

A new analysis of nearly 34,000 U.S. veterans suggests that taking nicotinamide, a widely available form of Vitamin B3, is linked to a meaningful reduction in non-melanoma skin cancers among people who have already had skin cancer. The biggest benefit was seen in those who started the supplement after their first cancer diagnosis. Participants who took 500 mg of nicotinamide twice daily for at least one month experienced about a 14% overall reduction in future skin cancers, with a striking 54% risk drop among those who began after their initial cancer. The cancers most affected were basal cell carcinoma and squamous cell carcinoma, the two most common non-melanoma forms. Importantly, the study did not assess melanoma.