#Noncaloric

New findings in Nature Metabolism show that non-caloric sweeteners may influence appetite signals in the brain, and responses vary by body weight. This adds depth to the idea that sugar substitutes are not a universal fix for weight management or diet-related health issues.

The study matters for Thailand, where sweetened beverages and snacks are common. Many people use zero- or low-calorie sweeteners to cut calories, but brain responses to these substitutes appear different among lean, overweight, and obese individuals. Practically, this could mean varying feelings of hunger or fullness after consuming these products, depending on weight status.