Eye health after mRNA vaccination: what Thai readers should know about recent corneal findings
A Turkish study reports a potential, short-term change in the cornea following Pfizer-BioNTech vaccination. Researchers observed small increases in corneal thickness and a decline in endothelial cell density after vaccination, but the changes were temporary and did not visibly affect vision in study participants.
The study tracked 64 adults who received the Pfizer vaccine, with imaging before the first dose and about two months after the second dose. The corneal endothelium kept the eye clear and showed an average thickness rise from 528 to 542 micrometers, about 2 percent, while endothelial cell density fell from roughly 2,597 to 2,378 cells per square millimeter, an 8 percent drop. Cells also showed more size variation and fewer hexagonal shapes, indicating cellular stress.