#Organaging

People with biologically “young” brains can expect to outlive their peers with “old” brains, according to groundbreaking research released by Stanford Medicine. The study, published in the prestigious journal Nature Medicine on July 9, offers the most comprehensive evidence to date that the biological age of individual organs—especially the brain—is a powerful predictor of health outcomes and lifespan. This discovery opens new possibilities for early intervention and preventive medicine, potentially transforming how Thais approach aging-related diseases such as dementia and heart disease.

A groundbreaking study from Stanford Medicine shows that people with biologically “younger” brains tend to live longer and healthier lives. Published in Nature Medicine, the research provides strong evidence that the biological age of organs, especially the brain, predicts health outcomes and lifespan. The findings offer new avenues for early interventions and preventive care, with potential relevance for aging-related diseases in Thailand.

Involving nearly 45,000 participants from the UK Biobank, researchers followed health outcomes over 17 years. They measured nearly 3,000 proteins in blood samples to estimate organ-specific biological ages, including the brain, heart, lungs, kidneys, and liver. These protein patterns were compared with age-matched norms to classify organs as “extremely aged” or “extremely youthful.”