New Study Links Depression to Antioxidant Deficits in the Brain
Groundbreaking neuroscience research published in the journal Psychopharmacology has revealed that individuals living with major depressive disorder show significantly lower levels of the antioxidant glutathione in the occipital cortex of the brain. This finding adds to a growing body of evidence suggesting that oxidative stress—including the subtle imbalance between damaging free radicals and the brain’s protective antioxidants—may be at the heart of depression’s complex biology (PsyPost).
This discovery is particularly meaningful in Thailand, where depression is becoming more widely recognized and discussed, yet biological risk factors remain less understood among the public. Mental health issues, including depression, are prevalent in the country, affecting individuals across various backgrounds, and contribute to personal suffering, economic loss, and significant stigma. Understanding the underlying biology of depression is thus not just academically interesting, but also a potential key to more effective prevention and treatment in Thai society.